PDE1A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0019933Biological processcAMP-mediated signaling
GO_0034391Biological processregulation of smooth muscle cell apoptotic process
GO_0046069Biological processcGMP catabolic process
GO_0048660Biological processregulation of smooth muscle cell proliferation
GO_0005829Cellular componentcytosol
GO_0043025Cellular componentneuronal cell body
GO_0004117Molecular functioncalmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity
GO_0005516Molecular functioncalmodulin binding
GO_0048101Molecular functioncalmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene namePDE1A
Protein namePhosphodiesterase 1A
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Cam-PDE 1A) (EC 3.1.4.17) (61 kDa Cam-PDE) (hCam-1)
Uncharacterized protein PDE1A
Calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
Synonyms
DescriptionFUNCTION: Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. .

AccessionsP54750
ENST00000358139.6 [P54750-3]
Q9Y246
ENST00000482782.6 [P54750-4]
Q9Y633
ENST00000410103.2 [P54750-1]
Q9UNL9
ENST00000495511.2 [P54750-1]
Q9Y634
ENST00000462938.6
Q53T15
ENST00000435564.6 [P54750-4]
Q53TB0
A0A8Q3WKY5
ENST00000409365.6 [P54750-6]
ENST00000351439.10 [P54750-2]