PCNT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0060271Biological processcilium assembly
GO_0090316Biological processpositive regulation of intracellular protein transport
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0007052Biological processmitotic spindle organization
GO_0005814Cellular componentcentriole
GO_0005813Cellular componentcentrosome
GO_0005829Cellular componentcytosol
GO_0005874Cellular componentmicrotubule
GO_0034451Cellular componentcentriolar satellite
GO_0016020Cellular componentmembrane
GO_0005516Molecular functioncalmodulin binding
GO_0005515Molecular functionprotein binding
GO_0060090Molecular functionmolecular adaptor activity

IV. Literature review

[source]
Gene namePCNT
Protein namePericentrin (Kendrin) (Pericentrin-B)
Pericentrin
PCNT protein
SynonymsPCNT2
KIAA0402
DescriptionFUNCTION: Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome. .

AccessionsENST00000490468.5
ENST00000359568.10 [O95613-1]
A0A8Q3SHZ3
H7C2A3
A0A8Q3SHV6
A0A8Q3SI04
ENST00000695530.1
ENST00000703224.1
ENST00000466474.6
O95613
ENST00000695526.1
A0A8Q3SHY5
ENST00000695528.1
A0A8V8TQ91
A0A8V8TQT6
ENST00000695558.1
Q8IWJ7
ENST00000480896.5 [O95613-2]
ENST00000418394.2
A0A8Q3SHZ8