PC | OmnibusX

Name	Number of supported studies	Average coverage
adipocyte	9 studies	38% ± 9%	Explore
hepatocyte	5 studies	49% ± 23%	Explore
astrocyte	5 studies	32% ± 10%	Explore
glutamatergic neuron	4 studies	30% ± 10%	Explore
oligodendrocyte	4 studies	21% ± 4%	Explore
GABAergic neuron	3 studies	28% ± 8%	Explore
interneuron	3 studies	24% ± 7%	Explore
oligodendrocyte precursor cell	3 studies	26% ± 8%	Explore

Name	Number of supported studies	Average coverage
brain	5 studies	25% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	5642.48	2640 / 2642	100%	45.73	703 / 705
liver	100%	21744.00	226 / 226	97%	80.43	394 / 406
breast	99%	6878.84	453 / 459	96%	20.33	1069 / 1118
adrenal gland	100%	5657.01	257 / 258	93%	20.18	213 / 230
prostate	91%	2091.48	222 / 245	99%	20.62	498 / 502
thymus	84%	1208.14	549 / 653	96%	30.28	582 / 605
kidney	97%	3990.64	86 / 89	79%	13.19	713 / 901
skin	77%	1385.41	1397 / 1809	93%	16.54	438 / 472
ovary	86%	1147.47	155 / 180	69%	7.25	297 / 430
stomach	80%	1559.44	287 / 359	68%	7.23	195 / 286
esophagus	49%	920.18	708 / 1445	90%	25.20	164 / 183
uterus	51%	557.16	87 / 170	86%	13.44	395 / 459
lung	46%	496.60	267 / 578	88%	18.40	1011 / 1155
intestine	45%	805.07	433 / 966	73%	7.58	386 / 527
pancreas	30%	302.27	97 / 328	84%	8.47	150 / 178
bladder	33%	368.38	7 / 21	67%	8.88	338 / 504
adipose	99%	8317.79	1192 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	21.77	44 / 45
eye	0%	0	0 / 0	94%	13.08	75 / 80
muscle	89%	1542.18	712 / 803	0%	0	0 / 0
blood vessel	70%	1072.83	941 / 1335	0%	0	0 / 0
heart	35%	378.22	300 / 861	0%	0	0 / 0
spleen	4%	66.70	10 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.22	1 / 29
peripheral blood	2%	15.15	15 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006739	Biological process	NADP metabolic process
GO_0006734	Biological process	NADH metabolic process
GO_0010629	Biological process	negative regulation of gene expression
GO_0006090	Biological process	pyruvate metabolic process
GO_0044794	Biological process	positive regulation by host of viral process
GO_0019074	Biological process	viral RNA genome packaging
GO_0006094	Biological process	gluconeogenesis
GO_0019076	Biological process	viral release from host cell
GO_0006629	Biological process	lipid metabolic process
GO_0005739	Cellular component	mitochondrion
GO_0005829	Cellular component	cytosol
GO_0005759	Cellular component	mitochondrial matrix
GO_0005737	Cellular component	cytoplasm
GO_0042802	Molecular function	identical protein binding
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding
GO_0004736	Molecular function	pyruvate carboxylase activity
GO_0009374	Molecular function	biotin binding
GO_0005515	Molecular function	protein binding

Gene name	PC
Protein name	Alternative protein PC Pyruvate carboxylase Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
Synonyms
Description	FUNCTION: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. .
Accessions	ENST00000393960.7 [P11498-1] ENST00000531614.6 L8E6S8 ENST00000524491.6 [P11498-2] A0A494BZT5 E9PRE7 ENST00000652125.1 [P11498-1] ENST00000628663.1 ENST00000528403.6 A0A494C101 ENST00000651036.1 [P11498-1] ENST00000393955.6 [P11498-1] P11498 ENST00000528224.2 ENST00000393958.7 [P11498-1] ENST00000651854.1 [P11498-1] ENST00000651469.1 A0A494C0T2 A0A494C016 ENST00000529047.6 [P11498-1]

PC report