Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 17 studies | 34% ± 16% | |
type I pneumocyte | 12 studies | 29% ± 10% | |
oligodendrocyte precursor cell | 12 studies | 32% ± 13% | |
macrophage | 11 studies | 23% ± 7% | |
oligodendrocyte | 11 studies | 31% ± 12% | |
endothelial cell | 10 studies | 26% ± 10% | |
astrocyte | 10 studies | 28% ± 13% | |
neuron | 9 studies | 34% ± 14% | |
glutamatergic neuron | 9 studies | 48% ± 24% | |
basal cell | 8 studies | 28% ± 11% | |
club cell | 7 studies | 27% ± 7% | |
GABAergic neuron | 7 studies | 39% ± 20% | |
plasma cell | 6 studies | 27% ± 8% | |
interneuron | 6 studies | 35% ± 18% | |
epithelial cell | 6 studies | 45% ± 25% | |
fibroblast | 6 studies | 20% ± 5% | |
myofibroblast cell | 5 studies | 20% ± 2% | |
connective tissue cell | 5 studies | 22% ± 4% | |
hematopoietic precursor cell | 4 studies | 32% ± 18% | |
secretory cell | 4 studies | 23% ± 8% | |
classical monocyte | 4 studies | 21% ± 4% | |
conventional dendritic cell | 4 studies | 25% ± 5% | |
dendritic cell | 4 studies | 24% ± 9% | |
monocyte | 4 studies | 21% ± 5% | |
alveolar macrophage | 4 studies | 26% ± 9% | |
mesothelial cell | 4 studies | 26% ± 14% | |
podocyte | 3 studies | 21% ± 4% | |
granule cell | 3 studies | 24% ± 4% | |
microglial cell | 3 studies | 20% ± 4% | |
myeloid cell | 3 studies | 33% ± 4% | |
serous secreting cell | 3 studies | 29% ± 8% | |
adipocyte | 3 studies | 25% ± 13% | |
non-classical monocyte | 3 studies | 25% ± 6% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 35% ± 15% | |
respiratory goblet cell | 3 studies | 34% ± 11% | |
hematopoietic stem cell | 3 studies | 23% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 4377.90 | 2641 / 2642 | 100% | 119.91 | 705 / 705 |
prostate | 100% | 2497.02 | 245 / 245 | 100% | 127.32 | 501 / 502 |
breast | 100% | 3213.22 | 459 / 459 | 100% | 124.91 | 1114 / 1118 |
pancreas | 100% | 3074.40 | 328 / 328 | 99% | 70.03 | 177 / 178 |
uterus | 100% | 2701.54 | 170 / 170 | 99% | 81.19 | 456 / 459 |
lung | 100% | 3180.51 | 577 / 578 | 99% | 69.52 | 1149 / 1155 |
ovary | 100% | 2294.27 | 180 / 180 | 99% | 57.04 | 427 / 430 |
intestine | 100% | 2041.94 | 966 / 966 | 99% | 52.66 | 522 / 527 |
stomach | 100% | 4046.03 | 359 / 359 | 99% | 50.19 | 283 / 286 |
bladder | 100% | 2421.33 | 21 / 21 | 99% | 65.35 | 498 / 504 |
esophagus | 100% | 2330.67 | 1443 / 1445 | 99% | 53.22 | 181 / 183 |
thymus | 100% | 1868.04 | 650 / 653 | 99% | 81.61 | 600 / 605 |
skin | 100% | 4480.58 | 1809 / 1809 | 98% | 108.73 | 464 / 472 |
kidney | 100% | 1980.69 | 89 / 89 | 95% | 47.50 | 860 / 901 |
adrenal gland | 94% | 1235.82 | 242 / 258 | 88% | 38.91 | 203 / 230 |
adipose | 100% | 2545.39 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 56.02 | 29 / 29 |
spleen | 100% | 1909.37 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 86.19 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 39.83 | 1 / 1 |
blood vessel | 100% | 2661.81 | 1331 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 53.75 | 77 / 80 |
peripheral blood | 91% | 2601.36 | 843 / 929 | 0% | 0 | 0 / 0 |
heart | 76% | 785.24 | 655 / 861 | 0% | 0 | 0 / 0 |
liver | 24% | 188.77 | 54 / 226 | 49% | 16.12 | 197 / 406 |
muscle | 17% | 127.75 | 137 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001501 | Biological process | skeletal system development |
GO_0050428 | Biological process | 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process |
GO_0000103 | Biological process | sulfate assimilation |
GO_0005829 | Cellular component | cytosol |
GO_0016779 | Molecular function | nucleotidyltransferase activity |
GO_0004781 | Molecular function | sulfate adenylyltransferase (ATP) activity |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0004020 | Molecular function | adenylylsulfate kinase activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | PAPSS1 |
Protein name | PAPSS1 protein Uncharacterized protein PAPSS1 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] |
Synonyms | ATPSK1 PAPSS |
Description | FUNCTION: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway . Required for normal biosynthesis of sulfated L-selectin ligands in endothelial cells . . |
Accessions | ENST00000265174.5 Q05BW9 O43252 Q4W5H3 Q4W5F0 |