Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 15 studies | 47% ± 20% | |
| ciliated cell | 14 studies | 36% ± 16% | |
| glutamatergic neuron | 12 studies | 57% ± 26% | |
| GABAergic neuron | 11 studies | 51% ± 28% | |
| oligodendrocyte precursor cell | 10 studies | 39% ± 10% | |
| microglial cell | 9 studies | 25% ± 7% | |
| interneuron | 6 studies | 49% ± 29% | |
| neuron | 5 studies | 40% ± 15% | |
| retinal ganglion cell | 5 studies | 55% ± 17% | |
| retinal bipolar neuron | 4 studies | 24% ± 8% | |
| GABAergic interneuron | 3 studies | 51% ± 16% | |
| OFF-bipolar cell | 3 studies | 37% ± 13% | |
| ON-bipolar cell | 3 studies | 32% ± 11% | |
| amacrine cell | 3 studies | 38% ± 16% | |
| ependymal cell | 3 studies | 46% ± 17% | |
| endothelial cell of lymphatic vessel | 3 studies | 20% ± 2% | |
| granule cell | 3 studies | 33% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 1901.21 | 2591 / 2642 | 100% | 11.24 | 703 / 705 |
| prostate | 82% | 502.99 | 202 / 245 | 95% | 2.76 | 475 / 502 |
| skin | 98% | 1811.82 | 1776 / 1809 | 65% | 2.38 | 307 / 472 |
| lung | 94% | 786.38 | 545 / 578 | 61% | 2.15 | 705 / 1155 |
| breast | 64% | 338.34 | 292 / 459 | 82% | 4.20 | 920 / 1118 |
| esophagus | 83% | 405.51 | 1202 / 1445 | 61% | 2.73 | 112 / 183 |
| liver | 73% | 386.46 | 166 / 226 | 44% | 1.11 | 177 / 406 |
| thymus | 80% | 339.79 | 524 / 653 | 22% | 0.60 | 131 / 605 |
| muscle | 100% | 5367.52 | 803 / 803 | 0% | 0 | 0 / 0 |
| adrenal gland | 9% | 44.98 | 22 / 258 | 91% | 8.09 | 209 / 230 |
| uterus | 41% | 133.38 | 70 / 170 | 58% | 2.30 | 267 / 459 |
| heart | 87% | 605.68 | 751 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 84% | 419.43 | 1127 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 2.36 | 37 / 45 |
| bladder | 57% | 254.00 | 12 / 21 | 21% | 0.62 | 108 / 504 |
| intestine | 60% | 244.03 | 580 / 966 | 17% | 0.48 | 87 / 527 |
| ovary | 42% | 164.21 | 75 / 180 | 16% | 0.35 | 68 / 430 |
| pancreas | 4% | 12.11 | 13 / 328 | 48% | 1.13 | 85 / 178 |
| stomach | 29% | 126.64 | 105 / 359 | 21% | 0.74 | 59 / 286 |
| kidney | 37% | 146.57 | 33 / 89 | 9% | 0.27 | 82 / 901 |
| adipose | 35% | 132.90 | 426 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.16 | 3 / 29 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.14 | 6 / 80 |
| spleen | 6% | 19.30 | 15 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 6.48 | 9 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006699 | Biological process | bile acid biosynthetic process |
| GO_0032374 | Biological process | regulation of cholesterol transport |
| GO_0006869 | Biological process | lipid transport |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0097038 | Cellular component | perinuclear endoplasmic reticulum |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005515 | Molecular function | protein binding |
| GO_0015485 | Molecular function | cholesterol binding |
| Gene name | OSBPL6 |
| Protein name | Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6) Alternative protein OSBPL6 OSBPL6 protein |
| Synonyms | ORP6 |
| Description | FUNCTION: Regulates cellular transport and efflux of cholesterol . Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal membrane (By similarity). Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid (By similarity). Weakly binds 25-hydroxycholesterol . . |
| Accessions | Q6PJ70 ENST00000315022.2 [Q9BZF3-3] ENST00000190611.9 [Q9BZF3-1] Q9BZF3 ENST00000359685.7 [Q9BZF3-2] ENST00000357080.8 [Q9BZF3-6] ENST00000409045.7 [Q9BZF3-4] ENST00000409631.5 [Q9BZF3-2] L8EBA8 L8ECL3 ENST00000392505.6 [Q9BZF3-5] |