OSBPL6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006699Biological processbile acid biosynthetic process
GO_0032374Biological processregulation of cholesterol transport
GO_0006869Biological processlipid transport
GO_0031901Cellular componentearly endosome membrane
GO_0005829Cellular componentcytosol
GO_0097038Cellular componentperinuclear endoplasmic reticulum
GO_0031965Cellular componentnuclear membrane
GO_0005886Cellular componentplasma membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding
GO_0015485Molecular functioncholesterol binding

IV. Literature review

[source]
Gene nameOSBPL6
Protein nameOxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6)
Alternative protein OSBPL6
OSBPL6 protein
SynonymsORP6
DescriptionFUNCTION: Regulates cellular transport and efflux of cholesterol . Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal membrane (By similarity). Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid (By similarity). Weakly binds 25-hydroxycholesterol . .

AccessionsQ6PJ70
ENST00000315022.2 [Q9BZF3-3]
ENST00000190611.9 [Q9BZF3-1]
Q9BZF3
ENST00000359685.7 [Q9BZF3-2]
ENST00000357080.8 [Q9BZF3-6]
ENST00000409045.7 [Q9BZF3-4]
ENST00000409631.5 [Q9BZF3-2]
L8EBA8
L8ECL3
ENST00000392505.6 [Q9BZF3-5]