Name | Number of supported studies | Average coverage | |
---|---|---|---|
renal alpha-intercalated cell | 6 studies | 45% ± 12% | |
kidney loop of Henle epithelial cell | 5 studies | 22% ± 5% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 46% ± 18% | |
GABAergic neuron | 4 studies | 31% ± 10% | |
brush cell | 4 studies | 38% ± 13% | |
glutamatergic neuron | 3 studies | 40% ± 12% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 26% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 19048.75 | 89 / 89 | 92% | 122.98 | 828 / 901 |
liver | 100% | 8623.39 | 226 / 226 | 84% | 39.49 | 340 / 406 |
thymus | 100% | 5812.50 | 651 / 653 | 67% | 18.45 | 408 / 605 |
brain | 96% | 5800.44 | 2530 / 2642 | 52% | 9.47 | 367 / 705 |
adrenal gland | 19% | 370.32 | 49 / 258 | 87% | 73.78 | 200 / 230 |
ovary | 4% | 37.87 | 8 / 180 | 84% | 16.39 | 360 / 430 |
eye | 0% | 0 | 0 / 0 | 63% | 9.76 | 50 / 80 |
prostate | 9% | 82.43 | 22 / 245 | 44% | 10.09 | 222 / 502 |
tonsil | 0% | 0 | 0 / 0 | 47% | 6.09 | 21 / 45 |
pancreas | 16% | 135.84 | 51 / 328 | 21% | 3.70 | 37 / 178 |
heart | 33% | 382.34 | 283 / 861 | 0% | 0 | 0 / 0 |
uterus | 7% | 74.06 | 12 / 170 | 23% | 4.61 | 107 / 459 |
stomach | 4% | 36.07 | 13 / 359 | 17% | 2.58 | 50 / 286 |
esophagus | 1% | 5.52 | 10 / 1445 | 17% | 2.36 | 32 / 183 |
lung | 0% | 0 | 0 / 578 | 18% | 2.45 | 207 / 1155 |
lymph node | 0% | 0 | 0 / 0 | 17% | 1.50 | 5 / 29 |
skin | 0% | 1.43 | 3 / 1809 | 14% | 2.16 | 66 / 472 |
intestine | 4% | 32.00 | 35 / 966 | 10% | 1.19 | 55 / 527 |
bladder | 0% | 0 | 0 / 21 | 14% | 1.63 | 69 / 504 |
peripheral blood | 6% | 77.67 | 56 / 929 | 0% | 0 | 0 / 0 |
breast | 0% | 1.98 | 1 / 459 | 5% | 0.56 | 51 / 1118 |
spleen | 0% | 10.30 | 1 / 241 | 0% | 0 | 0 / 0 |
adipose | 0% | 1.20 | 2 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006103 | Biological process | 2-oxoglutarate metabolic process |
GO_0006099 | Biological process | tricarboxylic acid cycle |
GO_0006096 | Biological process | glycolytic process |
GO_0045252 | Cellular component | oxoglutarate dehydrogenase complex |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0030976 | Molecular function | thiamine pyrophosphate binding |
GO_0004591 | Molecular function | oxoglutarate dehydrogenase (succinyl-transferring) activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | OGDHL |
Protein name | 2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like) |
Synonyms | KIAA1290 |
Description | FUNCTION: 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH (By similarity). The OGDHC complex is mainly active in the mitochondrion (By similarity). Involved in the inhibition of cell proliferation and in apoptosis . . |
Accessions | ENST00000432695.2 [Q9ULD0-3] ENST00000374103.9 [Q9ULD0-1] ENST00000419399.4 [Q9ULD0-2] Q9ULD0 |