I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 28% ± 4% | |
| glutamatergic neuron | 3 studies | 36% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 28% ± 4% | |
| glutamatergic neuron | 3 studies | 36% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 544.07 | 459 / 459 | 100% | 11.71 | 1116 / 1118 |
| bladder | 100% | 532.00 | 21 / 21 | 100% | 10.73 | 503 / 504 |
| esophagus | 100% | 421.32 | 1442 / 1445 | 100% | 9.09 | 183 / 183 |
| brain | 100% | 570.86 | 2632 / 2642 | 100% | 10.53 | 705 / 705 |
| uterus | 100% | 570.32 | 170 / 170 | 100% | 11.73 | 457 / 459 |
| ovary | 100% | 476.69 | 180 / 180 | 100% | 6.68 | 428 / 430 |
| lung | 99% | 372.72 | 573 / 578 | 100% | 8.87 | 1154 / 1155 |
| thymus | 100% | 414.50 | 652 / 653 | 99% | 9.07 | 600 / 605 |
| prostate | 100% | 429.35 | 245 / 245 | 99% | 5.61 | 496 / 502 |
| intestine | 100% | 464.89 | 966 / 966 | 98% | 11.26 | 519 / 527 |
| stomach | 99% | 287.66 | 356 / 359 | 99% | 10.46 | 284 / 286 |
| skin | 100% | 520.82 | 1807 / 1809 | 97% | 10.61 | 456 / 472 |
| kidney | 100% | 250.28 | 89 / 89 | 96% | 7.78 | 864 / 901 |
| pancreas | 97% | 189.68 | 318 / 328 | 99% | 8.46 | 176 / 178 |
| adrenal gland | 100% | 349.98 | 257 / 258 | 94% | 5.85 | 217 / 230 |
| liver | 99% | 201.22 | 224 / 226 | 74% | 3.46 | 299 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 13.40 | 29 / 29 |
| spleen | 100% | 604.99 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 9.02 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.05 | 1 / 1 |
| adipose | 100% | 539.17 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 343.30 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 292.20 | 851 / 861 | 0% | 0 | 0 / 0 |
| muscle | 98% | 270.92 | 786 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 4.61 | 71 / 80 |
| peripheral blood | 62% | 329.69 | 572 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051865 | Biological process | protein autoubiquitination |
| GO_0006513 | Biological process | protein monoubiquitination |
| GO_0006275 | Biological process | regulation of DNA replication |
| GO_0000785 | Cellular component | chromatin |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | OBI1 |
| Protein name | ORC ubiquitin ligase 1 (OBI1) (EC 2.3.2.27) (RING finger protein 219) |
| Synonyms | C13orf7 RNF219 |
| Description | FUNCTION: E3 ubiquitin ligase essential for DNA replication origin activation during S phase . Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase . . |
| Accessions | Q5W0B1 ENST00000282003.7 |
