NUGGC | OmnibusX

Name	Number of supported studies	Average coverage
plasma cell	4 studies	37% ± 10%	Explore
hepatocyte	3 studies	33% ± 11%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of NUGGC at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	1198.65	226 / 226	80%	10.12	323 / 406
lung	97%	109.98	560 / 578	55%	1.76	640 / 1155
thymus	98%	297.77	643 / 653	42%	1.74	254 / 605
kidney	96%	171.36	85 / 89	35%	1.60	317 / 901
stomach	69%	69.91	248 / 359	36%	1.18	104 / 286
ovary	77%	93.74	138 / 180	26%	0.50	112 / 430
spleen	100%	494.87	241 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	19.38	25 / 29
peripheral blood	81%	187.73	755 / 929	0%	0	0 / 0
intestine	54%	137.04	520 / 966	26%	0.71	135 / 527
breast	46%	32.00	209 / 459	29%	0.71	327 / 1118
bladder	43%	46.05	9 / 21	18%	0.41	90 / 504
esophagus	23%	13.13	337 / 1445	32%	1.01	59 / 183
tonsil	0%	0	0 / 0	56%	1.81	25 / 45
skin	27%	9.17	486 / 1809	27%	1.00	127 / 472
adipose	50%	42.77	603 / 1204	0%	0	0 / 0
pancreas	5%	1.94	17 / 328	35%	1.23	62 / 178
uterus	16%	5.92	28 / 170	18%	0.52	84 / 459
prostate	25%	16.51	62 / 245	3%	0.08	14 / 502
blood vessel	13%	6.81	168 / 1335	0%	0	0 / 0
adrenal gland	6%	2.20	16 / 258	0%	0.00	1 / 230
heart	6%	2.33	54 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	3%	0.04	2 / 80
brain	1%	0.20	14 / 2642	1%	0.02	7 / 705
muscle	0%	0.09	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071222	Biological process	cellular response to lipopolysaccharide
GO_0033262	Biological process	regulation of nuclear cell cycle DNA replication
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0016607	Cellular component	nuclear speck
GO_0005525	Molecular function	GTP binding
GO_0003924	Molecular function	GTPase activity

Gene name	NUGGC
Protein name	Nuclear GTPase, germinal center associated Nuclear GTPase SLIP-GC (EC 3.6.1.-) (Speckled-like pattern in the germinal center)
Synonyms	HMFN0672 C8orf80
Description	FUNCTION: Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA . Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). .
Accessions	ENST00000413272.7 C9JSP2 ENST00000418860.1 Q68CJ6

NUGGC report