NUDT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006139Biological processnucleobase-containing compound metabolic process
GO_0006915Biological processapoptotic process
GO_0034599Biological processcellular response to oxidative stress
GO_0006167Biological processAMP biosynthetic process
GO_0006754Biological processATP biosynthetic process
GO_0005759Cellular componentmitochondrial matrix
GO_0005525Molecular functionGTP binding
GO_0008803Molecular functionbis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
GO_0005515Molecular functionprotein binding
GO_0004081Molecular functionbis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity

IV. Literature review

[source]
Gene nameNUDT2
Protein nameBis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2)
SynonymsAPAH1
DescriptionFUNCTION: Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (By similarity). Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (By similarity). .

AccessionsENST00000618590.1
ENST00000379155.9
P50583
ENST00000346365.8
ENST00000379158.7