NSUN5 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	5 studies	26% ± 7%	Explore
naive B cell	5 studies	19% ± 4%	Explore
B cell	4 studies	19% ± 5%	Explore
hematopoietic precursor cell	4 studies	21% ± 4%	Explore
precursor B cell	3 studies	27% ± 8%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of NSUN5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1344.13	1445 / 1445	100%	32.46	183 / 183
ovary	100%	1052.78	180 / 180	100%	33.33	430 / 430
uterus	100%	1518.31	170 / 170	100%	38.28	459 / 459
thymus	100%	1309.91	653 / 653	100%	28.37	603 / 605
skin	100%	1417.34	1809 / 1809	100%	42.62	470 / 472
stomach	100%	1092.06	359 / 359	99%	34.22	284 / 286
intestine	100%	1560.77	966 / 966	99%	37.49	523 / 527
breast	100%	1277.95	459 / 459	99%	30.04	1108 / 1118
liver	100%	759.11	226 / 226	99%	22.98	402 / 406
pancreas	100%	1170.24	328 / 328	99%	27.53	176 / 178
prostate	100%	1443.43	245 / 245	99%	28.34	495 / 502
kidney	100%	1151.47	89 / 89	99%	21.64	888 / 901
lung	99%	1138.01	575 / 578	99%	30.94	1143 / 1155
adrenal gland	100%	971.24	258 / 258	98%	19.20	225 / 230
bladder	100%	1513.90	21 / 21	98%	34.77	492 / 504
brain	100%	1068.75	2636 / 2642	92%	20.17	652 / 705
adipose	100%	1118.69	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	36.72	80 / 80
lymph node	0%	0	0 / 0	100%	73.90	29 / 29
muscle	100%	1617.78	803 / 803	0%	0	0 / 0
spleen	100%	2247.92	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	33.46	45 / 45
ureter	0%	0	0 / 0	100%	16.53	1 / 1
blood vessel	100%	1108.13	1334 / 1335	0%	0	0 / 0
peripheral blood	99%	2040.07	920 / 929	0%	0	0 / 0
heart	99%	814.26	850 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0050890	Biological process	cognition
GO_0014003	Biological process	oligodendrocyte development
GO_0021987	Biological process	cerebral cortex development
GO_0031641	Biological process	regulation of myelination
GO_0070475	Biological process	rRNA base methylation
GO_0022038	Biological process	corpus callosum development
GO_0045727	Biological process	positive regulation of translation
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0009383	Molecular function	rRNA (cytosine-C5-)-methyltransferase activity
GO_0003723	Molecular function	RNA binding

Gene name	NSUN5
Protein name	28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1-related protein) (NOL1R) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein) NOP2/Sun RNA methyltransferase 5
Synonyms	WBSCR20 NSUN5A WBSCR20A
Description	FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 (m5C3782) in 28S rRNA . m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity . Required for corpus callosum and cerebral cortex development (By similarity). .
Accessions	H7C2G6 ENST00000310326.8 [Q96P11-4] ENST00000252594.10 [Q96P11-1] ENST00000438747.7 [Q96P11-2] Q96P11 ENST00000428206.5 [Q96P11-5] ENST00000455763.1

NSUN5 report