Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 9 studies | 31% ± 14% | |
GABAergic neuron | 8 studies | 39% ± 24% | |
astrocyte | 8 studies | 32% ± 14% | |
glutamatergic neuron | 7 studies | 46% ± 27% | |
microglial cell | 7 studies | 27% ± 9% | |
dendritic cell | 7 studies | 25% ± 10% | |
endothelial cell | 6 studies | 28% ± 10% | |
macrophage | 6 studies | 29% ± 11% | |
interneuron | 5 studies | 43% ± 22% | |
myeloid cell | 5 studies | 21% ± 5% | |
oligodendrocyte | 5 studies | 25% ± 6% | |
neuron | 4 studies | 35% ± 16% | |
epithelial cell | 4 studies | 25% ± 12% | |
classical monocyte | 3 studies | 20% ± 1% | |
GABAergic interneuron | 3 studies | 23% ± 3% | |
alveolar macrophage | 3 studies | 29% ± 8% | |
monocyte | 3 studies | 25% ± 5% | |
transit amplifying cell | 3 studies | 32% ± 23% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 11 studies | 33% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2568.38 | 1445 / 1445 | 100% | 23.68 | 183 / 183 |
intestine | 100% | 2797.21 | 966 / 966 | 100% | 21.98 | 527 / 527 |
prostate | 100% | 2464.29 | 245 / 245 | 100% | 24.59 | 502 / 502 |
lung | 100% | 2454.34 | 578 / 578 | 100% | 21.32 | 1154 / 1155 |
bladder | 100% | 3050.00 | 21 / 21 | 100% | 21.18 | 503 / 504 |
thymus | 100% | 2374.92 | 653 / 653 | 100% | 24.07 | 603 / 605 |
stomach | 100% | 2163.09 | 359 / 359 | 100% | 21.00 | 285 / 286 |
skin | 100% | 3395.59 | 1809 / 1809 | 100% | 28.15 | 470 / 472 |
breast | 100% | 2684.61 | 459 / 459 | 99% | 22.63 | 1112 / 1118 |
pancreas | 100% | 1882.34 | 328 / 328 | 99% | 16.58 | 177 / 178 |
brain | 99% | 1677.18 | 2619 / 2642 | 100% | 21.15 | 704 / 705 |
uterus | 100% | 2595.80 | 170 / 170 | 99% | 17.82 | 454 / 459 |
ovary | 100% | 2239.84 | 180 / 180 | 99% | 13.26 | 424 / 430 |
adrenal gland | 100% | 2718.62 | 258 / 258 | 98% | 14.37 | 226 / 230 |
kidney | 100% | 1355.87 | 89 / 89 | 98% | 15.24 | 880 / 901 |
liver | 76% | 472.24 | 171 / 226 | 61% | 5.46 | 249 / 406 |
adipose | 100% | 2992.53 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2428.43 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 24.30 | 29 / 29 |
spleen | 100% | 3217.79 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 17.07 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.38 | 1 / 1 |
muscle | 100% | 1936.06 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 1464.97 | 841 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 2357.10 | 897 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 30.52 | 77 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_1905038 | Biological process | regulation of membrane lipid metabolic process |
GO_0006672 | Biological process | ceramide metabolic process |
GO_0034250 | Biological process | positive regulation of amide metabolic process |
GO_0043065 | Biological process | positive regulation of apoptotic process |
GO_0045834 | Biological process | positive regulation of lipid metabolic process |
GO_0033209 | Biological process | tumor necrosis factor-mediated signaling pathway |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0016230 | Molecular function | sphingomyelin phosphodiesterase activator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | NSMAF |
Protein name | Neutral sphingomyelinase activation associated factor Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation) |
Synonyms | FAN |
Description | FUNCTION: Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N-smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE. |
Accessions | E5RGF5 Q92636 ENST00000427130.6 [Q92636-2] E5RGU2 ENST00000518159.5 ENST00000038176.8 [Q92636-1] ENST00000518229.5 ENST00000649465.1 |