Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 6 studies | 23% ± 7% | |
| natural killer cell | 5 studies | 20% ± 3% | |
| non-classical monocyte | 5 studies | 23% ± 7% | |
| neutrophil | 4 studies | 24% ± 6% | |
| conventional dendritic cell | 4 studies | 25% ± 12% | |
| epithelial cell | 4 studies | 37% ± 14% | |
| fibroblast | 4 studies | 21% ± 4% | |
| glutamatergic neuron | 4 studies | 29% ± 12% | |
| macrophage | 3 studies | 24% ± 4% | |
| myeloid cell | 3 studies | 25% ± 4% | |
| monocyte | 3 studies | 24% ± 5% | |
| ciliated cell | 3 studies | 24% ± 6% | |
| endothelial cell | 3 studies | 19% ± 5% | |
| dendritic cell | 3 studies | 36% ± 10% | |
| naive B cell | 3 studies | 20% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| peripheral blood | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1419.18 | 459 / 459 | 100% | 43.28 | 1118 / 1118 |
| esophagus | 100% | 887.32 | 1445 / 1445 | 100% | 40.52 | 183 / 183 |
| ovary | 100% | 725.99 | 180 / 180 | 100% | 36.34 | 430 / 430 |
| intestine | 100% | 995.61 | 966 / 966 | 100% | 34.74 | 526 / 527 |
| uterus | 100% | 1030.29 | 170 / 170 | 100% | 41.47 | 458 / 459 |
| liver | 100% | 1975.88 | 226 / 226 | 100% | 32.63 | 405 / 406 |
| lung | 100% | 1103.03 | 577 / 578 | 100% | 44.56 | 1154 / 1155 |
| stomach | 100% | 738.18 | 359 / 359 | 100% | 34.36 | 285 / 286 |
| bladder | 100% | 904.24 | 21 / 21 | 100% | 34.69 | 502 / 504 |
| prostate | 100% | 801.37 | 244 / 245 | 100% | 26.83 | 501 / 502 |
| thymus | 100% | 963.33 | 653 / 653 | 99% | 31.51 | 601 / 605 |
| skin | 100% | 1556.31 | 1809 / 1809 | 99% | 40.50 | 468 / 472 |
| kidney | 100% | 697.55 | 89 / 89 | 99% | 26.83 | 893 / 901 |
| pancreas | 98% | 500.91 | 323 / 328 | 100% | 37.75 | 178 / 178 |
| brain | 98% | 712.93 | 2589 / 2642 | 100% | 31.07 | 705 / 705 |
| adrenal gland | 100% | 792.47 | 258 / 258 | 97% | 20.20 | 224 / 230 |
| adipose | 100% | 1505.79 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 53.19 | 29 / 29 |
| spleen | 100% | 1736.04 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 40.60 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.24 | 1 / 1 |
| muscle | 100% | 1249.05 | 801 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 790.69 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 3291.90 | 921 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 33.90 | 78 / 80 |
| heart | 97% | 602.00 | 832 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006914 | Biological process | autophagy |
| GO_0034976 | Biological process | response to endoplasmic reticulum stress |
| GO_0035032 | Cellular component | phosphatidylinositol 3-kinase complex, class III |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0005776 | Cellular component | autophagosome |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NRBF2 |
| Protein name | Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR) |
| Synonyms | COPR |
| Description | FUNCTION: May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). .; FUNCTION: Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy . Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 (By similarity). Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1 . May be involved in autophagosome biogenesis . May play a role in neural progenitor cell survival during differentiation (By similarity). . |
| Accessions | ENST00000435510.6 [Q96F24-3] ENST00000277746.11 [Q96F24-1] Q96F24 |