NOL6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NOL6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NOL6 at tissue level.

III. Associated gene sets

GO_0006364Biological processrRNA processing
GO_0006409Biological processtRNA export from nucleus
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0034456Cellular componentUTP-C complex
GO_0000794Cellular componentcondensed nuclear chromosome
GO_0005739Cellular componentmitochondrion
GO_0005654Cellular componentnucleoplasm
GO_0032545Cellular componentCURI complex
GO_0032040Cellular componentsmall-subunit processome
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameNOL6
Protein nameNucleolar protein 6
Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap)
Synonyms
DescriptionFUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. .

FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. .

AccessionsENST00000297990.9 [Q9H6R4-1]
ENST00000379470.5
A0A0C4DFX0
ENST00000379471.3
ENST00000353159.6 [Q9H6R4-3]
Q9H6R4
A0A0A0MRW6