I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 19% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 19% ± 5% |
Insufficient scRNA-seq data for expression of NOL12 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| uterus | 100% | 1739.86 | 170 / 170 | 98% | 3.51 | 449 / 459 |
| bladder | 100% | 1491.29 | 21 / 21 | 97% | 3.74 | 488 / 504 |
| esophagus | 100% | 1614.46 | 1445 / 1445 | 96% | 2.08 | 176 / 183 |
| pancreas | 100% | 790.76 | 327 / 328 | 94% | 3.28 | 167 / 178 |
| intestine | 100% | 1616.51 | 966 / 966 | 93% | 3.26 | 491 / 527 |
| skin | 100% | 1359.38 | 1809 / 1809 | 92% | 3.11 | 436 / 472 |
| brain | 100% | 1513.01 | 2639 / 2642 | 90% | 2.69 | 635 / 705 |
| lung | 100% | 1162.15 | 577 / 578 | 90% | 2.96 | 1034 / 1155 |
| adrenal gland | 100% | 2005.91 | 258 / 258 | 89% | 2.11 | 204 / 230 |
| thymus | 100% | 1944.34 | 653 / 653 | 88% | 2.58 | 531 / 605 |
| prostate | 100% | 1966.93 | 245 / 245 | 85% | 2.07 | 427 / 502 |
| breast | 100% | 1218.12 | 459 / 459 | 84% | 1.90 | 944 / 1118 |
| stomach | 100% | 1208.33 | 359 / 359 | 83% | 2.40 | 236 / 286 |
| ovary | 100% | 1532.35 | 180 / 180 | 67% | 1.36 | 286 / 430 |
| kidney | 100% | 1363.40 | 89 / 89 | 63% | 1.66 | 571 / 901 |
| liver | 100% | 680.70 | 225 / 226 | 50% | 1.07 | 201 / 406 |
| adipose | 100% | 1074.95 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 4.27 | 29 / 29 |
| spleen | 100% | 2209.74 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.76 | 1 / 1 |
| blood vessel | 100% | 947.31 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 800.26 | 856 / 861 | 0% | 0 | 0 / 0 |
| muscle | 97% | 620.44 | 781 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 1198.42 | 902 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 2.52 | 42 / 45 |
| eye | 0% | 0 | 0 / 0 | 69% | 1.51 | 55 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0019843 | Molecular function | rRNA binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003723 | Molecular function | RNA binding |
| GO_0003697 | Molecular function | single-stranded DNA binding |
| Gene name | NOL12 |
| Protein name | Alternative protein NOL12 Nucleolar protein 12 |
| Synonyms | |
| Description | FUNCTION: Multifunctional RNA binding protein that plays a role in RNA metabolism and DNA maintenance. Participates in the resolution of DNA stress and the maintenance of genome integrity by localizing to sites of DNA insults . Plays also a role in proper nucleolar organization by limiting nucleolar size and regulating nucleolar number. Mechanistically, regulates the nucleolar levels of fibrillarin and nucleolin, two key players in pre-rRNA processing and ribosome assembly . . |
| Accessions | ENST00000611699.1 ENST00000359114.9 L8E965 ENST00000438329.5 Q9UGY1 |
