NME6 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NME6 at tissue level.

III. Associated gene sets

GO_0006183Biological processGTP biosynthetic process
GO_0006915Biological processapoptotic process
GO_0030308Biological processnegative regulation of cell growth
GO_0045839Biological processnegative regulation of mitotic nuclear division
GO_0006228Biological processUTP biosynthetic process
GO_0006241Biological processCTP biosynthetic process
GO_0005759Cellular componentmitochondrial matrix
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0004550Molecular functionnucleoside diphosphate kinase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameNME6
Protein nameNucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha) (nm23-H6)
Nucleoside diphosphate kinase (EC 2.7.4.6)
NME/NM23 nucleoside diphosphate kinase 6
SynonymshCG_1779448
DescriptionFUNCTION: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.

AccessionsENST00000643457.1 [O75414-1]
ENST00000421967.5
A0A0C4DG91
ENST00000444069.5
ENST00000425930.5
ENST00000435684.5 [O75414-3]
ENST00000415644.5 [O75414-2]
C9J9V6
ENST00000454531.1
ENST00000426689.6 [O75414-1]
ENST00000642710.1
C9JQB1
ENST00000643011.1
C9J1J2
ENST00000456495.5
A0A2R8Y7V2
ENST00000447724.1
ENST00000442597.6 [O75414-1]
ENST00000452211.5 [O75414-1]
ENST00000447314.5
ENST00000451657.6 [O75414-3]
F2Z2J2
O75414
A0A2R8Y547
C9J867
ENST00000418431.5
ENST00000415053.5 [O75414-1]