I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 23% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 23% ± 6% |
Insufficient scRNA-seq data for expression of NAGLU at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 3229.89 | 226 / 226 | 100% | 62.27 | 406 / 406 |
| pancreas | 100% | 2903.66 | 328 / 328 | 100% | 52.35 | 178 / 178 |
| thymus | 100% | 3887.70 | 653 / 653 | 100% | 64.22 | 604 / 605 |
| esophagus | 100% | 1826.13 | 1442 / 1445 | 100% | 31.35 | 183 / 183 |
| kidney | 100% | 3492.49 | 89 / 89 | 100% | 62.30 | 899 / 901 |
| prostate | 100% | 2946.20 | 245 / 245 | 100% | 75.32 | 500 / 502 |
| uterus | 100% | 2913.96 | 170 / 170 | 100% | 40.68 | 457 / 459 |
| skin | 100% | 2288.51 | 1806 / 1809 | 100% | 72.22 | 470 / 472 |
| stomach | 100% | 2556.32 | 359 / 359 | 99% | 35.29 | 284 / 286 |
| intestine | 100% | 2318.73 | 966 / 966 | 99% | 41.98 | 523 / 527 |
| lung | 100% | 3094.57 | 577 / 578 | 99% | 41.22 | 1146 / 1155 |
| bladder | 100% | 2751.81 | 21 / 21 | 99% | 46.39 | 498 / 504 |
| adrenal gland | 100% | 3555.57 | 258 / 258 | 99% | 46.74 | 227 / 230 |
| breast | 100% | 3484.37 | 459 / 459 | 99% | 41.28 | 1102 / 1118 |
| ovary | 100% | 3177.54 | 180 / 180 | 97% | 22.35 | 418 / 430 |
| brain | 88% | 747.77 | 2337 / 2642 | 100% | 44.42 | 704 / 705 |
| adipose | 100% | 3529.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3603.38 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 117.23 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 51.05 | 29 / 29 |
| spleen | 100% | 3665.90 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 32.43 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 27.50 | 1 / 1 |
| heart | 96% | 1189.66 | 824 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 85% | 1085.96 | 786 / 929 | 0% | 0 | 0 / 0 |
| muscle | 84% | 840.72 | 677 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007040 | Biological process | lysosome organization |
| GO_0035640 | Biological process | exploration behavior |
| GO_0030202 | Biological process | heparin metabolic process |
| GO_0097577 | Biological process | sequestering of iron ion |
| GO_0001774 | Biological process | microglial cell activation |
| GO_0097696 | Biological process | cell surface receptor signaling pathway via STAT |
| GO_0001573 | Biological process | ganglioside metabolic process |
| GO_0021675 | Biological process | nerve development |
| GO_0007028 | Biological process | cytoplasm organization |
| GO_0061744 | Biological process | motor behavior |
| GO_0045475 | Biological process | locomotor rhythm |
| GO_0008340 | Biological process | determination of adult lifespan |
| GO_0003183 | Biological process | mitral valve morphogenesis |
| GO_0048143 | Biological process | astrocyte activation |
| GO_0046548 | Biological process | retinal rod cell development |
| GO_0055013 | Biological process | cardiac muscle cell development |
| GO_0060173 | Biological process | limb development |
| GO_0031069 | Biological process | hair follicle morphogenesis |
| GO_0016485 | Biological process | protein processing |
| GO_0001889 | Biological process | liver development |
| GO_0060586 | Biological process | multicellular organismal-level iron ion homeostasis |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0034285 | Biological process | response to disaccharide |
| GO_1904389 | Biological process | rod bipolar cell differentiation |
| GO_0030201 | Biological process | heparan sulfate proteoglycan metabolic process |
| GO_0007030 | Biological process | Golgi organization |
| GO_0034599 | Biological process | cellular response to oxidative stress |
| GO_0003220 | Biological process | left ventricular cardiac muscle tissue morphogenesis |
| GO_0014004 | Biological process | microglia differentiation |
| GO_1904390 | Biological process | cone retinal bipolar cell differentiation |
| GO_0030200 | Biological process | heparan sulfate proteoglycan catabolic process |
| GO_0003158 | Biological process | endothelium development |
| GO_0035909 | Biological process | aorta morphogenesis |
| GO_0034142 | Biological process | toll-like receptor 4 signaling pathway |
| GO_0035633 | Biological process | maintenance of blood-brain barrier |
| GO_0030534 | Biological process | adult behavior |
| GO_0060119 | Biological process | inner ear receptor cell development |
| GO_0006914 | Biological process | autophagy |
| GO_0042474 | Biological process | middle ear morphogenesis |
| GO_0006801 | Biological process | superoxide metabolic process |
| GO_0042982 | Biological process | amyloid precursor protein metabolic process |
| GO_0009611 | Biological process | response to wounding |
| GO_0042445 | Biological process | hormone metabolic process |
| GO_0071407 | Biological process | cellular response to organic cyclic compound |
| GO_0007399 | Biological process | nervous system development |
| GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
| GO_0032963 | Biological process | collagen metabolic process |
| GO_0021680 | Biological process | cerebellar Purkinje cell layer development |
| GO_0044242 | Biological process | cellular lipid catabolic process |
| GO_0099022 | Biological process | vesicle tethering |
| GO_0005764 | Cellular component | lysosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0043202 | Cellular component | lysosomal lumen |
| GO_0004561 | Molecular function | alpha-N-acetylglucosaminidase activity |
| Gene name | NAGLU |
| Protein name | N-acetyl-alpha-glucosaminidase Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] Alpha-N-acetylglucosaminidase (N-acetylglucosaminidase, alpha-(Sanfilippo disease IIIB), isoform CRA_a) |
| Synonyms | ufHSD2 UFHSD1 hCG_16571 |
| Description | FUNCTION: Involved in the degradation of heparan sulfate. |
| Accessions | ENST00000590358.1 ENST00000586516.5 ENST00000225927.7 Q14769 K7EQH9 K7END1 P54802 A0A286RZ41 K7ENX5 K7ESD7 A0A286RZ43 ENST00000592454.1 A0A286RZ40 ENST00000591587.1 |
