Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 6 studies | 30% ± 11% | |
plasmacytoid dendritic cell | 6 studies | 19% ± 2% | |
CD16-positive, CD56-dim natural killer cell, human | 5 studies | 17% ± 2% | |
classical monocyte | 5 studies | 20% ± 4% | |
oligodendrocyte | 5 studies | 23% ± 4% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 16% ± 1% | |
non-classical monocyte | 3 studies | 24% ± 5% | |
endothelial cell | 3 studies | 24% ± 5% | |
glutamatergic neuron | 3 studies | 28% ± 9% | |
natural killer cell | 3 studies | 17% ± 1% | |
basal cell | 3 studies | 28% ± 12% | |
astrocyte | 3 studies | 25% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5940.62 | 1445 / 1445 | 100% | 17.62 | 183 / 183 |
prostate | 100% | 8023.31 | 245 / 245 | 100% | 13.02 | 502 / 502 |
lung | 100% | 6681.70 | 578 / 578 | 100% | 14.41 | 1154 / 1155 |
intestine | 100% | 7098.30 | 966 / 966 | 100% | 16.94 | 526 / 527 |
bladder | 100% | 7645.05 | 21 / 21 | 100% | 24.92 | 503 / 504 |
ovary | 100% | 5446.07 | 180 / 180 | 100% | 11.59 | 429 / 430 |
thymus | 100% | 6353.96 | 653 / 653 | 100% | 13.14 | 603 / 605 |
stomach | 100% | 4452.45 | 359 / 359 | 100% | 14.52 | 285 / 286 |
breast | 100% | 4988.46 | 459 / 459 | 100% | 13.65 | 1114 / 1118 |
skin | 100% | 5182.74 | 1809 / 1809 | 100% | 12.21 | 470 / 472 |
kidney | 100% | 5111.25 | 89 / 89 | 100% | 13.42 | 897 / 901 |
pancreas | 100% | 2868.98 | 327 / 328 | 99% | 15.36 | 177 / 178 |
liver | 100% | 4210.25 | 226 / 226 | 99% | 8.26 | 402 / 406 |
uterus | 100% | 5465.61 | 170 / 170 | 99% | 14.12 | 454 / 459 |
brain | 97% | 2761.14 | 2568 / 2642 | 100% | 9.26 | 704 / 705 |
adrenal gland | 100% | 5425.02 | 258 / 258 | 97% | 7.42 | 222 / 230 |
adipose | 100% | 4808.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 9.79 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 20.95 | 29 / 29 |
spleen | 100% | 9972.71 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.24 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 20.75 | 1 / 1 |
blood vessel | 100% | 4298.89 | 1332 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 7548.93 | 923 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 2291.52 | 843 / 861 | 0% | 0 | 0 / 0 |
muscle | 73% | 1112.31 | 586 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0009435 | Biological process | NAD biosynthetic process |
GO_0034627 | Biological process | 'de novo' NAD biosynthetic process |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004359 | Molecular function | glutaminase activity |
GO_0003952 | Molecular function | NAD+ synthase (glutamine-hydrolyzing) activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | NADSYN1 |
Protein name | Glutamine-dependent NAD(+) synthetase (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) NAD synthetase 1 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) |
Synonyms | |
Description | FUNCTION: Catalyzes the final step of the nicotinamide adenine dinucleotide (NAD) de novo synthesis pathway, the ATP-dependent amidation of deamido-NAD using L-glutamine as a nitrogen source. . |
Accessions | ENST00000525200.5 ENST00000529840.5 ENST00000525593.5 E9PNF5 H0YDH3 ENST00000319023.7 [Q6IA69-1] Q6IA69 ENST00000529120.5 E9PKY6 ENST00000527852.6 E9PND0 H0YCQ6 A0A0B4J216 H0YCF9 H0YED2 ENST00000527963.1 ENST00000530055.5 ENST00000528509.5 |