Insufficient scRNA-seq data for expression of MYLK2 at single-cell level.
Insufficient scRNA-seq data for expression of MYLK2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 96% | 112.83 | 2533 / 2642 | 99% | 5.10 | 696 / 705 |
pancreas | 100% | 575.87 | 327 / 328 | 35% | 1.36 | 62 / 178 |
muscle | 100% | 29514.46 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 201.71 | 240 / 241 | 0% | 0 | 0 / 0 |
thymus | 65% | 49.72 | 424 / 653 | 23% | 2.10 | 139 / 605 |
stomach | 63% | 35.61 | 227 / 359 | 5% | 0.06 | 13 / 286 |
blood vessel | 68% | 115.72 | 902 / 1335 | 0% | 0 | 0 / 0 |
heart | 61% | 40.82 | 525 / 861 | 0% | 0 | 0 / 0 |
intestine | 54% | 31.47 | 517 / 966 | 5% | 0.09 | 24 / 527 |
uterus | 27% | 20.95 | 46 / 170 | 30% | 2.23 | 136 / 459 |
ovary | 19% | 13.55 | 34 / 180 | 35% | 0.89 | 149 / 430 |
esophagus | 39% | 26.74 | 568 / 1445 | 5% | 0.08 | 10 / 183 |
lung | 25% | 12.93 | 144 / 578 | 6% | 0.13 | 65 / 1155 |
tonsil | 0% | 0 | 0 / 0 | 27% | 0.88 | 12 / 45 |
bladder | 10% | 6.57 | 2 / 21 | 14% | 0.24 | 71 / 504 |
breast | 11% | 25.68 | 51 / 459 | 12% | 0.26 | 139 / 1118 |
prostate | 18% | 30.31 | 44 / 245 | 5% | 0.27 | 25 / 502 |
skin | 19% | 44.82 | 336 / 1809 | 4% | 0.10 | 19 / 472 |
peripheral blood | 22% | 53.03 | 209 / 929 | 0% | 0 | 0 / 0 |
adipose | 19% | 15.59 | 234 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 5% | 1.48 | 12 / 258 | 6% | 0.08 | 13 / 230 |
kidney | 6% | 3.72 | 5 / 89 | 4% | 0.08 | 37 / 901 |
liver | 4% | 1.61 | 8 / 226 | 1% | 0.08 | 5 / 406 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006941 | Biological process | striated muscle contraction |
GO_0014816 | Biological process | skeletal muscle satellite cell differentiation |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0018107 | Biological process | peptidyl-threonine phosphorylation |
GO_0032971 | Biological process | regulation of muscle filament sliding |
GO_0007274 | Biological process | neuromuscular synaptic transmission |
GO_0060048 | Biological process | cardiac muscle contraction |
GO_0055008 | Biological process | cardiac muscle tissue morphogenesis |
GO_0035914 | Biological process | skeletal muscle cell differentiation |
GO_0046777 | Biological process | protein autophosphorylation |
GO_0030017 | Cellular component | sarcomere |
GO_0045202 | Cellular component | synapse |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005524 | Molecular function | ATP binding |
GO_0004683 | Molecular function | calmodulin-dependent protein kinase activity |
GO_0004687 | Molecular function | myosin light chain kinase activity |
GO_0005516 | Molecular function | calmodulin binding |
GO_0032027 | Molecular function | myosin light chain binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MYLK2 |
Protein name | Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) (EC 2.7.11.18) |
Synonyms | |
Description | FUNCTION: Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain. . |
Accessions | Q9H1R3 ENST00000375994.6 ENST00000375985.5 |