Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 18 studies | 20% ± 5% | |
CD16-positive, CD56-dim natural killer cell, human | 10 studies | 25% ± 5% | |
CD16-negative, CD56-bright natural killer cell, human | 8 studies | 21% ± 4% | |
retinal ganglion cell | 6 studies | 43% ± 26% | |
epithelial cell | 6 studies | 26% ± 7% | |
endothelial cell | 4 studies | 23% ± 3% | |
glutamatergic neuron | 4 studies | 39% ± 20% | |
type II pneumocyte | 4 studies | 26% ± 14% | |
GABAergic neuron | 4 studies | 27% ± 10% | |
mature NK T cell | 3 studies | 19% ± 4% | |
amacrine cell | 3 studies | 21% ± 2% | |
ciliated cell | 3 studies | 18% ± 1% | |
CD8-positive, alpha-beta T cell | 3 studies | 18% ± 2% | |
dendritic cell | 3 studies | 21% ± 3% | |
basal cell | 3 studies | 24% ± 4% | |
goblet cell | 3 studies | 21% ± 2% | |
neuron | 3 studies | 25% ± 5% |
Insufficient scRNA-seq data for expression of MVD at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 1975.32 | 170 / 170 | 100% | 34.78 | 457 / 459 |
thymus | 100% | 2671.60 | 652 / 653 | 100% | 22.01 | 602 / 605 |
brain | 100% | 3396.78 | 2636 / 2642 | 100% | 39.04 | 702 / 705 |
esophagus | 100% | 3512.42 | 1443 / 1445 | 99% | 22.42 | 182 / 183 |
prostate | 100% | 2712.85 | 245 / 245 | 99% | 31.09 | 498 / 502 |
intestine | 100% | 2632.42 | 966 / 966 | 99% | 41.66 | 521 / 527 |
adrenal gland | 100% | 4763.28 | 258 / 258 | 99% | 59.18 | 227 / 230 |
liver | 100% | 3986.06 | 225 / 226 | 99% | 40.10 | 402 / 406 |
pancreas | 98% | 1367.40 | 323 / 328 | 100% | 35.37 | 178 / 178 |
stomach | 100% | 2370.11 | 358 / 359 | 99% | 30.37 | 282 / 286 |
bladder | 100% | 1830.52 | 21 / 21 | 98% | 36.88 | 495 / 504 |
skin | 100% | 3570.05 | 1808 / 1809 | 98% | 23.84 | 462 / 472 |
lung | 100% | 3786.23 | 577 / 578 | 98% | 28.91 | 1130 / 1155 |
kidney | 100% | 2420.34 | 89 / 89 | 97% | 16.08 | 875 / 901 |
breast | 100% | 1741.81 | 458 / 459 | 94% | 19.78 | 1050 / 1118 |
ovary | 100% | 2047.06 | 180 / 180 | 91% | 12.26 | 391 / 430 |
lymph node | 0% | 0 | 0 / 0 | 100% | 66.18 | 29 / 29 |
spleen | 100% | 2770.68 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 32.83 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 43.75 | 1 / 1 |
adipose | 100% | 1957.43 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 1547.54 | 1325 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 1406.27 | 830 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 17.90 | 77 / 80 |
muscle | 94% | 1109.21 | 757 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 91% | 2554.46 | 845 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008299 | Biological process | isoprenoid biosynthetic process |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0006695 | Biological process | cholesterol biosynthetic process |
GO_0019287 | Biological process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
GO_0005829 | Cellular component | cytosol |
GO_0005777 | Cellular component | peroxisome |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0004163 | Molecular function | diphosphomevalonate decarboxylase activity |
GO_0030544 | Molecular function | Hsp70 protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | MVD |
Protein name | Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase) Mevalonate diphosphate decarboxylase Diphosphomevalonate decarboxylase (Mevalonate (diphospho)decarboxylase) (Mevalonate pyrophosphate decarboxylase) |
Synonyms | MPD |
Description | FUNCTION: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. . FUNCTION: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. . |
Accessions | ENST00000565610.5 ENST00000301012.8 H3BP35 ENST00000568133.5 H3BQ47 H3BVC4 ENST00000567064.5 H3BRZ1 ENST00000569177.5 P53602 |