Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 10 studies | 26% ± 11% | |
epithelial cell | 6 studies | 35% ± 15% | |
ciliated cell | 6 studies | 28% ± 7% | |
myofibroblast cell | 5 studies | 19% ± 3% | |
fibroblast | 5 studies | 25% ± 9% | |
classical monocyte | 4 studies | 22% ± 4% | |
connective tissue cell | 4 studies | 30% ± 12% | |
pericyte | 4 studies | 24% ± 5% | |
non-classical monocyte | 3 studies | 22% ± 3% | |
vein endothelial cell | 3 studies | 22% ± 7% | |
smooth muscle cell | 3 studies | 19% ± 2% | |
endothelial cell of lymphatic vessel | 3 studies | 21% ± 4% | |
abnormal cell | 3 studies | 21% ± 3% | |
macrophage | 3 studies | 23% ± 1% | |
dendritic cell | 3 studies | 30% ± 6% | |
goblet cell | 3 studies | 20% ± 4% | |
plasmacytoid dendritic cell | 3 studies | 20% ± 6% | |
basal cell | 3 studies | 33% ± 11% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 4 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1680.61 | 1445 / 1445 | 100% | 26.15 | 183 / 183 |
ovary | 100% | 2958.63 | 180 / 180 | 100% | 66.59 | 430 / 430 |
thymus | 100% | 2490.91 | 653 / 653 | 100% | 52.59 | 605 / 605 |
uterus | 100% | 1789.37 | 170 / 170 | 100% | 45.17 | 459 / 459 |
stomach | 100% | 1341.47 | 359 / 359 | 100% | 32.99 | 285 / 286 |
skin | 100% | 2053.29 | 1809 / 1809 | 100% | 48.70 | 470 / 472 |
intestine | 100% | 1523.52 | 966 / 966 | 99% | 34.61 | 523 / 527 |
prostate | 100% | 1524.32 | 245 / 245 | 99% | 28.65 | 498 / 502 |
brain | 99% | 661.31 | 2620 / 2642 | 100% | 37.94 | 705 / 705 |
breast | 100% | 2079.49 | 459 / 459 | 99% | 38.46 | 1105 / 1118 |
pancreas | 100% | 1065.95 | 327 / 328 | 99% | 33.88 | 176 / 178 |
bladder | 100% | 1485.86 | 21 / 21 | 98% | 39.86 | 496 / 504 |
lung | 100% | 1462.78 | 577 / 578 | 99% | 30.30 | 1138 / 1155 |
kidney | 100% | 1855.12 | 89 / 89 | 98% | 36.02 | 882 / 901 |
adrenal gland | 100% | 2700.29 | 258 / 258 | 97% | 29.61 | 223 / 230 |
liver | 100% | 950.69 | 226 / 226 | 96% | 24.73 | 391 / 406 |
adipose | 100% | 1945.26 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 58.48 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 34.40 | 29 / 29 |
spleen | 100% | 1705.84 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 41.06 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 37.26 | 1 / 1 |
blood vessel | 100% | 1512.09 | 1332 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 777.57 | 792 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 760.19 | 849 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 924.19 | 887 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0039702 | Biological process | viral budding via host ESCRT complex |
GO_0036258 | Biological process | multivesicular body assembly |
GO_0046755 | Biological process | viral budding |
GO_0016236 | Biological process | macroautophagy |
GO_0043162 | Biological process | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
GO_0042058 | Biological process | regulation of epidermal growth factor receptor signaling pathway |
GO_0090148 | Biological process | membrane fission |
GO_0032510 | Biological process | endosome to lysosome transport via multivesicular body sorting pathway |
GO_0019075 | Biological process | virus maturation |
GO_0032801 | Biological process | receptor catabolic process |
GO_0043328 | Biological process | protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
GO_0031902 | Cellular component | late endosome membrane |
GO_0005813 | Cellular component | centrosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0000813 | Cellular component | ESCRT I complex |
GO_0005829 | Cellular component | cytosol |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0010008 | Cellular component | endosome membrane |
GO_0031982 | Cellular component | vesicle |
GO_0005634 | Cellular component | nucleus |
GO_0043130 | Molecular function | ubiquitin binding |
GO_0008289 | Molecular function | lipid binding |
GO_0005515 | Molecular function | protein binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | MVB12A |
Protein name | Multivesicular body subunit 12A (CIN85/CD2AP family-binding protein) (ESCRT-I complex subunit MVB12A) (Protein FAM125A) Multivesicular body subunit 12A Multivesicular body subunit 12A (ESCRT-I complex subunit MVB12A) (Protein FAM125A) |
Synonyms | FAM125A CFBP |
Description | FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor. . |
Accessions | ENST00000528515.5 ENST00000594784.1 ENST00000600514.5 Q96EY5 ENST00000528911.5 E9PLL0 E9PQA6 E9PLZ8 ENST00000528604.5 M0QZK6 ENST00000529939.5 ENST00000317040.12 [Q96EY5-1] E9PJW8 |