MTRFR | OmnibusX

Name	Number of supported studies	Average coverage
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	19% ± 1%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
epithelial cell	4 studies	28% ± 6%	Explore
CD8-positive, alpha-beta T cell	4 studies	17% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
B cell	3 studies	21% ± 2%	Explore
fibroblast	3 studies	23% ± 4%	Explore
endothelial cell	3 studies	18% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	17% ± 2%	Explore
gamma-delta T cell	3 studies	24% ± 13%	Explore

Name	Number of supported studies	Average coverage
liver	3 studies	26% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1163.62	258 / 258	100%	12.24	230 / 230
bladder	100%	1170.62	21 / 21	100%	10.73	504 / 504
esophagus	100%	1131.83	1445 / 1445	100%	7.84	183 / 183
intestine	100%	1157.26	966 / 966	100%	8.46	527 / 527
kidney	100%	991.94	89 / 89	100%	10.01	901 / 901
ovary	100%	1261.87	180 / 180	100%	10.24	430 / 430
prostate	100%	1768.33	245 / 245	100%	12.89	502 / 502
stomach	100%	924.33	359 / 359	100%	7.71	286 / 286
thymus	100%	1172.98	653 / 653	100%	17.94	605 / 605
uterus	100%	1601.43	170 / 170	100%	14.15	459 / 459
breast	100%	1021.82	459 / 459	100%	9.57	1117 / 1118
lung	100%	950.40	577 / 578	100%	11.13	1155 / 1155
brain	100%	1014.61	2636 / 2642	100%	13.85	705 / 705
liver	100%	727.32	226 / 226	100%	6.79	404 / 406
skin	100%	929.35	1807 / 1809	99%	9.20	468 / 472
pancreas	98%	484.56	323 / 328	99%	8.42	176 / 178
adipose	100%	831.23	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	10.64	29 / 29
spleen	100%	1186.61	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	13.62	45 / 45
ureter	0%	0	0 / 0	100%	5.84	1 / 1
muscle	100%	685.94	802 / 803	0%	0	0 / 0
blood vessel	100%	885.58	1332 / 1335	0%	0	0 / 0
heart	98%	722.81	848 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	88%	4.34	70 / 80
peripheral blood	69%	512.44	641 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0072344	Biological process	rescue of stalled ribosome
GO_0006415	Biological process	translational termination
GO_0005739	Cellular component	mitochondrion
GO_0043023	Molecular function	ribosomal large subunit binding
GO_0000049	Molecular function	tRNA binding
GO_0005515	Molecular function	protein binding
GO_0003747	Molecular function	translation release factor activity

Gene name	MTRFR
Protein name	Mitochondrial translation release factor in rescue Probable peptide chain release factor C12orf65, mitochondrial
Synonyms	C12orf65 My030
Description	FUNCTION: Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation . As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue . .
Accessions	ENST00000546132.2 [Q9H3J6-2] ENST00000546132 ENST00000679849.1 [Q9H3J6-1] ENST00000543139 ENST00000680325.1 [Q9H3J6-2] F5GWJ6 ENST00000366329.7 [Q9H3J6-1] ENST00000429587.2 [Q9H3J6-1] F5H4X5 F5H5V8 Q9H3J6 ENST00000538888.6 [Q9H3J6-2] ENST00000543139.2 [Q9H3J6-1] ENST00000536130 ENST00000253233.6 [Q9H3J6-1] ENST00000425637.3 [Q9H3J6-2] ENST00000536130.2 [Q9H3J6-1]

MTRFR report