Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 12 studies | 38% ± 14% | |
endothelial cell | 11 studies | 26% ± 9% | |
pericyte | 6 studies | 21% ± 8% | |
endothelial cell of lymphatic vessel | 6 studies | 32% ± 13% | |
fibroblast | 5 studies | 21% ± 11% | |
astrocyte | 5 studies | 31% ± 13% | |
glutamatergic neuron | 5 studies | 46% ± 24% | |
oligodendrocyte precursor cell | 5 studies | 27% ± 9% | |
epithelial cell | 4 studies | 22% ± 2% | |
adipocyte | 4 studies | 18% ± 3% | |
ciliated cell | 4 studies | 24% ± 6% | |
smooth muscle cell | 4 studies | 17% ± 1% | |
microglial cell | 3 studies | 18% ± 1% | |
macrophage | 3 studies | 25% ± 10% | |
GABAergic neuron | 3 studies | 52% ± 10% | |
interneuron | 3 studies | 46% ± 21% | |
neuron | 3 studies | 31% ± 13% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 9 studies | 35% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2280.95 | 1445 / 1445 | 100% | 14.16 | 183 / 183 |
ovary | 100% | 2160.86 | 180 / 180 | 100% | 9.53 | 430 / 430 |
uterus | 100% | 2194.33 | 170 / 170 | 100% | 9.99 | 458 / 459 |
lung | 100% | 2426.56 | 577 / 578 | 100% | 12.14 | 1154 / 1155 |
prostate | 100% | 2315.89 | 244 / 245 | 100% | 13.00 | 502 / 502 |
brain | 100% | 2068.85 | 2630 / 2642 | 100% | 13.24 | 705 / 705 |
bladder | 100% | 2417.81 | 21 / 21 | 99% | 10.26 | 500 / 504 |
intestine | 100% | 2120.99 | 966 / 966 | 99% | 9.62 | 522 / 527 |
thymus | 100% | 1855.22 | 653 / 653 | 99% | 7.35 | 599 / 605 |
stomach | 100% | 1717.94 | 359 / 359 | 99% | 10.55 | 283 / 286 |
kidney | 100% | 2292.52 | 89 / 89 | 99% | 13.34 | 891 / 901 |
breast | 100% | 2375.91 | 459 / 459 | 99% | 10.29 | 1103 / 1118 |
skin | 100% | 2059.63 | 1806 / 1809 | 98% | 15.18 | 462 / 472 |
pancreas | 96% | 865.58 | 314 / 328 | 98% | 10.61 | 175 / 178 |
adrenal gland | 100% | 1568.93 | 258 / 258 | 94% | 6.60 | 216 / 230 |
adipose | 100% | 2804.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3542.37 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1399.66 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 7.44 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.36 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 98% | 10.25 | 78 / 80 |
heart | 97% | 1365.08 | 836 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 7.38 | 28 / 29 |
muscle | 92% | 644.29 | 742 / 803 | 0% | 0 | 0 / 0 |
liver | 29% | 155.88 | 65 / 226 | 52% | 2.55 | 211 / 406 |
peripheral blood | 40% | 853.33 | 367 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0031642 | Biological process | negative regulation of myelination |
GO_2000643 | Biological process | positive regulation of early endosome to late endosome transport |
GO_2000645 | Biological process | negative regulation of receptor catabolic process |
GO_0045806 | Biological process | negative regulation of endocytosis |
GO_0032288 | Biological process | myelin assembly |
GO_0046856 | Biological process | phosphatidylinositol dephosphorylation |
GO_0048666 | Biological process | neuron development |
GO_0090394 | Biological process | negative regulation of excitatory postsynaptic potential |
GO_0097062 | Biological process | dendritic spine maintenance |
GO_0002091 | Biological process | negative regulation of receptor internalization |
GO_0060304 | Biological process | regulation of phosphatidylinositol dephosphorylation |
GO_0006661 | Biological process | phosphatidylinositol biosynthetic process |
GO_0043197 | Cellular component | dendritic spine |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0016020 | Cellular component | membrane |
GO_0097060 | Cellular component | synaptic membrane |
GO_0031901 | Cellular component | early endosome membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0030425 | Cellular component | dendrite |
GO_0005829 | Cellular component | cytosol |
GO_0008021 | Cellular component | synaptic vesicle |
GO_0014069 | Cellular component | postsynaptic density |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005774 | Cellular component | vacuolar membrane |
GO_0030424 | Cellular component | axon |
GO_0005634 | Cellular component | nucleus |
GO_0004438 | Molecular function | phosphatidylinositol-3-phosphate phosphatase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0008138 | Molecular function | protein tyrosine/serine/threonine phosphatase activity |
GO_0052629 | Molecular function | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | MTMR2 |
Protein name | Myotubularin related protein 2 Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Myotubularin-related protein 2 (EC 3.1.3.64) (EC 3.1.3.95) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (Phosphatidylinositol-3-phosphate phosphatase) |
Synonyms | KIAA1073 |
Description | FUNCTION: Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate . Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (By similarity). Stabilizes SBF2/MTMR13 at the membranes (By similarity). Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (By similarity). . |
Accessions | A0A6Q8PF46 ENST00000676268.1 ENST00000676177.1 ENST00000393223.8 [Q13614-2] ENST00000676440.1 [Q13614-2] ENST00000675981.1 [Q13614-2] ENST00000675636.1 [Q13614-2] Q13614 ENST00000481642.6 [Q13614-2] ENST00000675196.1 [Q13614-2] ENST00000409459.5 [Q13614-2] ENST00000676261.1 [Q13614-2] C9JEX3 A0A6Q8PFL3 ENST00000674989.1 [Q13614-2] ENST00000675660.1 ENST00000676388.1 ENST00000676272.1 [Q13614-2] ENST00000674974.1 ENST00000444541.7 [Q13614-2] ENST00000675288.1 ENST00000470293.6 [Q13614-2] ENST00000675174.1 [Q13614-2] ENST00000444541 ENST00000674950.1 ENST00000675910.1 ENST00000675022.1 ENST00000675652.1 [Q13614-2] ENST00000675320.1 ENST00000676146.1 ENST00000676378.1 [Q13614-2] ENST00000674610.1 [Q13614-2] A0A6Q8PGV9 ENST00000675848.1 A0A6Q8PHC4 ENST00000675896.1 ENST00000674528.1 [Q13614-2] A0A6Q8PGS5 ENST00000674924.1 [Q13614-2] ENST00000346299.10 [Q13614-1] ENST00000675922.1 ENST00000675362.1 [Q13614-2] ENST00000495134.6 [Q13614-2] A0A6Q8PHL9 ENST00000675030.1 ENST00000675933.1 [Q13614-2] ENST00000497683.6 [Q13614-2] A0A6Q8PG25 ENST00000675489.1 [Q13614-2] ENST00000484818.6 [Q13614-2] ENST00000674968.1 [Q13614-2] ENST00000675454.1 [Q13614-2] ENST00000675477.1 [Q13614-2] ENST00000676027.1 ENST00000675438.1 A0A6Q8PGT1 A0A6Q8PHS7 ENST00000352297.11 [Q13614-2] ENST00000675807.1 ENST00000676166.1 [Q13614-2] |