MTHFD2L report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046655Biological processfolic acid metabolic process
GO_0006164Biological processpurine nucleotide biosynthetic process
GO_0000105Biological processL-histidine biosynthetic process
GO_0009086Biological processmethionine biosynthetic process
GO_0035999Biological processtetrahydrofolate interconversion
GO_0005759Cellular componentmitochondrial matrix
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0004477Molecular functionmethenyltetrahydrofolate cyclohydrolase activity
GO_0004487Molecular functionmethylenetetrahydrofolate dehydrogenase (NAD+) activity
GO_0004488Molecular functionmethylenetetrahydrofolate dehydrogenase (NADP+) activity

IV. Literature review

[source]
Gene nameMTHFD2L
Protein nameMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
MTHFD2L protein (Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like)
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein) (MTHFD2-like) [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15) (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]
Synonyms
DescriptionFUNCTION: Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. .

AccessionsQ8IY64
F8W7P9
ENST00000325278.7 [Q9H903-4]
ENST00000395759.6 [Q9H903-4]
ENST00000359107.10
Q9H903
ENST00000423607.6
ENST00000429335.5