MTERF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006393Biological processtermination of mitochondrial transcription
GO_0032392Biological processDNA geometric change
GO_0006353Biological processDNA-templated transcription termination
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005739Cellular componentmitochondrion
GO_0005759Cellular componentmitochondrial matrix
GO_0042645Cellular componentmitochondrial nucleoid
GO_0003690Molecular functiondouble-stranded DNA binding
GO_0005515Molecular functionprotein binding
GO_0003676Molecular functionnucleic acid binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameMTERF1
Protein nameMitochondrial transcription termination factor 1 (cDNA FLJ51270, highly similar to Transcription termination factor, mitochondrial)
Mitochondrial transcription termination factor 1
Transcription termination factor 1, mitochondrial (Mitochondrial transcription termination factor 1) (mTERF) (mTERF1)
SynonymsMTERF
DescriptionFUNCTION: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand. .

FUNCTION: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand. .

FUNCTION: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand. .

FUNCTION: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand. .

AccessionsENST00000351870.8
C9JNM8
ENST00000456229.1
ENST00000419292.1
C9JE25
B4DPR9
C9JU79
ENST00000442961.1
Q99551
ENST00000406735.6
ENST00000425936.1