Name | Number of supported studies | Average coverage | |
---|---|---|---|
GABAergic neuron | 3 studies | 30% ± 4% | |
glutamatergic neuron | 3 studies | 34% ± 2% |
Insufficient scRNA-seq data for expression of MSH4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 98% | 85.04 | 177 / 180 | 6% | 0.12 | 26 / 430 |
muscle | 98% | 93.92 | 788 / 803 | 0% | 0 | 0 / 0 |
uterus | 96% | 80.92 | 164 / 170 | 2% | 0.03 | 7 / 459 |
lung | 93% | 55.37 | 536 / 578 | 4% | 0.07 | 50 / 1155 |
intestine | 91% | 54.06 | 879 / 966 | 6% | 0.17 | 31 / 527 |
spleen | 97% | 58.80 | 233 / 241 | 0% | 0 | 0 / 0 |
bladder | 90% | 84.76 | 19 / 21 | 4% | 0.10 | 19 / 504 |
blood vessel | 94% | 59.13 | 1256 / 1335 | 0% | 0 | 0 / 0 |
prostate | 91% | 51.11 | 224 / 245 | 1% | 0.02 | 7 / 502 |
breast | 88% | 47.24 | 402 / 459 | 4% | 0.07 | 43 / 1118 |
brain | 83% | 59.30 | 2181 / 2642 | 3% | 0.06 | 22 / 705 |
adipose | 84% | 39.69 | 1014 / 1204 | 0% | 0 | 0 / 0 |
heart | 82% | 38.06 | 710 / 861 | 0% | 0 | 0 / 0 |
esophagus | 74% | 39.67 | 1071 / 1445 | 4% | 0.16 | 7 / 183 |
thymus | 76% | 27.82 | 494 / 653 | 1% | 0.01 | 6 / 605 |
stomach | 65% | 25.06 | 233 / 359 | 6% | 0.12 | 16 / 286 |
adrenal gland | 61% | 18.52 | 158 / 258 | 8% | 0.13 | 18 / 230 |
kidney | 62% | 21.89 | 55 / 89 | 6% | 0.14 | 54 / 901 |
skin | 50% | 16.31 | 904 / 1809 | 4% | 0.10 | 19 / 472 |
pancreas | 38% | 10.59 | 125 / 328 | 3% | 0.05 | 5 / 178 |
liver | 22% | 6.86 | 50 / 226 | 4% | 0.05 | 15 / 406 |
peripheral blood | 17% | 4.54 | 158 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 4% | 0.11 | 3 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007131 | Biological process | reciprocal meiotic recombination |
GO_0007283 | Biological process | spermatogenesis |
GO_0006298 | Biological process | mismatch repair |
GO_0007292 | Biological process | female gamete generation |
GO_0007129 | Biological process | homologous chromosome pairing at meiosis |
GO_0001541 | Biological process | ovarian follicle development |
GO_0005694 | Cellular component | chromosome |
GO_0000795 | Cellular component | synaptonemal complex |
GO_0005713 | Cellular component | recombination nodule |
GO_0005634 | Cellular component | nucleus |
GO_0003690 | Molecular function | double-stranded DNA binding |
GO_0003677 | Molecular function | DNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0030983 | Molecular function | mismatched DNA binding |
GO_0005524 | Molecular function | ATP binding |
GO_0140664 | Molecular function | ATP-dependent DNA damage sensor activity |
Gene name | MSH4 |
Protein name | MutS protein homolog 4 (hMSH4) MutS homolog 4 |
Synonyms | |
Description | FUNCTION: Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis. |
Accessions | ENST00000263187.4 O15457 Q5ZEZ0 |