MRM3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MRM3 at tissue level.

III. Associated gene sets

GO_0000451Biological processrRNA 2'-O-methylation
GO_0005739Cellular componentmitochondrion
GO_0005759Cellular componentmitochondrial matrix
GO_0070039Molecular functionrRNA (guanosine-2'-O-)-methyltransferase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameMRM3
Protein nameMitochondrial rRNA methyltransferase 3
rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1)
SynonymsRNMTL1
HC90
DescriptionFUNCTION: S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. .

AccessionsI3L443
Q9HC36
ENST00000574509.1
I3L0T6
ENST00000571157.1
ENST00000304478.9