Insufficient scRNA-seq data for expression of MRM1 at single-cell level.
Insufficient scRNA-seq data for expression of MRM1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 372.12 | 1443 / 1445 | 100% | 12.15 | 183 / 183 |
intestine | 100% | 461.32 | 966 / 966 | 100% | 23.86 | 526 / 527 |
pancreas | 100% | 296.38 | 327 / 328 | 100% | 17.06 | 178 / 178 |
thymus | 100% | 410.68 | 653 / 653 | 100% | 15.96 | 603 / 605 |
bladder | 100% | 532.38 | 21 / 21 | 100% | 24.23 | 502 / 504 |
uterus | 100% | 406.17 | 170 / 170 | 100% | 16.92 | 457 / 459 |
skin | 99% | 349.06 | 1799 / 1809 | 100% | 21.57 | 472 / 472 |
kidney | 100% | 381.37 | 89 / 89 | 99% | 15.32 | 896 / 901 |
prostate | 100% | 458.44 | 245 / 245 | 99% | 14.33 | 499 / 502 |
stomach | 100% | 311.33 | 358 / 359 | 100% | 21.04 | 285 / 286 |
brain | 99% | 264.57 | 2623 / 2642 | 100% | 13.25 | 704 / 705 |
liver | 99% | 312.99 | 224 / 226 | 100% | 14.50 | 405 / 406 |
breast | 100% | 367.74 | 459 / 459 | 98% | 14.94 | 1100 / 1118 |
adrenal gland | 100% | 497.13 | 258 / 258 | 98% | 12.12 | 225 / 230 |
ovary | 100% | 441.91 | 180 / 180 | 98% | 9.79 | 420 / 430 |
lung | 96% | 263.90 | 557 / 578 | 100% | 16.63 | 1151 / 1155 |
eye | 0% | 0 | 0 / 0 | 100% | 27.15 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 39.55 | 29 / 29 |
muscle | 100% | 408.81 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 525.92 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 12.95 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 25.82 | 1 / 1 |
blood vessel | 100% | 283.38 | 1331 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 303.06 | 1198 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 328.37 | 844 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 83% | 310.05 | 770 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000154 | Biological process | rRNA modification |
GO_0000451 | Biological process | rRNA 2'-O-methylation |
GO_0005739 | Cellular component | mitochondrion |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0070039 | Molecular function | rRNA (guanosine-2'-O-)-methyltransferase activity |
GO_0016435 | Molecular function | rRNA (guanine) methyltransferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | MRM1 |
Protein name | Mitochondrial rRNA methyltransferase 1 (rRNA methyltransferase 1, mitochondrial) rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1145)-2'-O)-methyltransferase) (16S rRNA [Gm1145] 2'-O-methyltransferase) |
Synonyms | hCG_30203 |
Description | FUNCTION: S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145 (Gm1145) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. . |
Accessions | ENST00000614766.5 [Q6IN84-1] Q6IN84 ENST00000612760.1 ENST00000611231.2 [Q6IN84-1] A0A087WZC1 ENST00000631971.1 |