Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 12 studies | 28% ± 7% |
Insufficient scRNA-seq data for expression of MORN3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 98% | 151.46 | 640 / 653 | 87% | 2.53 | 529 / 605 |
| brain | 92% | 304.63 | 2432 / 2642 | 71% | 3.39 | 504 / 705 |
| kidney | 94% | 116.42 | 84 / 89 | 68% | 2.18 | 612 / 901 |
| breast | 71% | 72.66 | 324 / 459 | 87% | 3.74 | 974 / 1118 |
| lung | 95% | 228.39 | 548 / 578 | 60% | 2.20 | 693 / 1155 |
| ovary | 67% | 63.00 | 121 / 180 | 77% | 2.08 | 332 / 430 |
| uterus | 63% | 72.19 | 107 / 170 | 69% | 3.34 | 316 / 459 |
| pancreas | 35% | 23.95 | 116 / 328 | 85% | 2.22 | 151 / 178 |
| skin | 87% | 269.15 | 1578 / 1809 | 16% | 0.33 | 77 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.46 | 1 / 1 |
| bladder | 52% | 37.24 | 11 / 21 | 47% | 1.76 | 236 / 504 |
| spleen | 98% | 130.88 | 237 / 241 | 0% | 0 | 0 / 0 |
| prostate | 64% | 53.68 | 157 / 245 | 21% | 0.35 | 104 / 502 |
| peripheral blood | 78% | 99.32 | 720 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 1.59 | 20 / 29 |
| stomach | 42% | 25.26 | 150 / 359 | 19% | 0.71 | 55 / 286 |
| intestine | 40% | 36.44 | 383 / 966 | 21% | 0.81 | 109 / 527 |
| adrenal gland | 7% | 4.05 | 17 / 258 | 51% | 1.39 | 117 / 230 |
| adipose | 55% | 37.35 | 661 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 2.16 | 24 / 45 |
| esophagus | 16% | 9.26 | 227 / 1445 | 30% | 1.03 | 55 / 183 |
| blood vessel | 23% | 15.79 | 308 / 1335 | 0% | 0 | 0 / 0 |
| heart | 22% | 14.44 | 192 / 861 | 0% | 0 | 0 / 0 |
| liver | 1% | 0.42 | 2 / 226 | 9% | 0.41 | 37 / 406 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.06 | 3 / 80 |
| muscle | 0% | 0.84 | 4 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1901797 | Biological process | negative regulation of signal transduction by p53 class mediator |
| GO_0001669 | Cellular component | acrosomal vesicle |
| GO_0005634 | Cellular component | nucleus |
| GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MORN3 |
| Protein name | MORN repeat-containing protein 3 |
| Synonyms | |
| Description | FUNCTION: Assembles a suppression complex (suppresome) by tethering SIRT1 and MDM2 to regulate composite modifications of p53/TP53. Confers both deacetylation-mediated functional inactivation, by SIRT1, and ubiquitination-dependent degradation, by MDM2, of p53/TP53, promoting a proliferative and cell survival behaviors . May play a role in the regulation of spermatogenesis (By similarity). . |
| Accessions | ENST00000392462.6 [Q6PF18-2] ENST00000355329.7 [Q6PF18-1] ENST00000542364.1 [Q6PF18-2] Q6PF18 |