MON1A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MON1A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MON1A at tissue level.

III. Associated gene sets

GO_0006623Biological processprotein targeting to vacuole
GO_0016192Biological processvesicle-mediated transport
GO_0009306Biological processprotein secretion
GO_0005829Cellular componentcytosol
GO_0035658Cellular componentMon1-Ccz1 complex
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMON1A
Protein nameVacuolar fusion protein MON1 homolog A
Vacuolar fusion protein MON1 homolog
SynonymsSAND1
DescriptionFUNCTION: Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form . .

FUNCTION: Plays an important role in membrane trafficking through the secretory apparatus. .

AccessionsENST00000296473.8 [Q86VX9-5]
Q86VX9
A0A0A0MSQ9
ENST00000417270.2 [Q86VX9-5]
ENST00000642691.1 [Q86VX9-5]
ENST00000455683.7 [Q86VX9-2]
ENST00000417270
ENST00000645862.1 [Q86VX9-5]