MMRN2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MMRN2 at tissue level.

III. Associated gene sets

GO_0002042Biological processcell migration involved in sprouting angiogenesis
GO_0090051Biological processnegative regulation of cell migration involved in sprouting angiogenesis
GO_0030336Biological processnegative regulation of cell migration
GO_0008285Biological processnegative regulation of cell population proliferation
GO_1905278Biological processpositive regulation of epithelial tube formation
GO_1903588Biological processnegative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO_0030948Biological processnegative regulation of vascular endothelial growth factor receptor signaling pathway
GO_0007155Biological processcell adhesion
GO_1900426Biological processpositive regulation of defense response to bacterium
GO_1905332Biological processpositive regulation of morphogenesis of an epithelium
GO_0005604Cellular componentbasement membrane
GO_0005615Cellular componentextracellular space
GO_1990972Cellular componentmultimerin complex
GO_0070062Cellular componentextracellular exosome
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005201Molecular functionextracellular matrix structural constituent
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMMRN2
Protein nameAlternative protein MMRN2
Multimerin 2
Multimerin-2 (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit)
SynonymsEMILIN3
DescriptionFUNCTION: Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it down-regulates KDR activation by binding VEGFA. .

AccessionsENST00000474994.2
V9GYS9
V9GY37
R4GMY6
ENST00000608090.1
ENST00000609457.5
L8E8T6
Q9H8L6
ENST00000610081.5
ENST00000372027.10
V9GY43