Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| natural killer cell | 4 studies | 24% ± 6% | |
| CD16-positive, CD56-dim natural killer cell, human | 3 studies | 30% ± 6% | |
| endothelial cell | 3 studies | 23% ± 4% | |
| epithelial cell | 3 studies | 32% ± 17% | |
| glutamatergic neuron | 3 studies | 23% ± 5% |
Insufficient scRNA-seq data for expression of MEX3C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1265.88 | 2636 / 2642 | 100% | 28.30 | 704 / 705 |
| lung | 100% | 1847.81 | 577 / 578 | 100% | 18.58 | 1152 / 1155 |
| esophagus | 100% | 1637.67 | 1445 / 1445 | 99% | 20.23 | 182 / 183 |
| ovary | 100% | 2050.58 | 180 / 180 | 99% | 16.93 | 427 / 430 |
| breast | 100% | 2159.23 | 459 / 459 | 99% | 22.92 | 1105 / 1118 |
| thymus | 100% | 1843.47 | 653 / 653 | 99% | 24.15 | 596 / 605 |
| stomach | 100% | 1355.50 | 359 / 359 | 98% | 14.75 | 280 / 286 |
| bladder | 100% | 1650.00 | 21 / 21 | 98% | 15.45 | 492 / 504 |
| intestine | 100% | 1787.20 | 966 / 966 | 98% | 13.86 | 514 / 527 |
| prostate | 100% | 1481.58 | 245 / 245 | 97% | 13.20 | 488 / 502 |
| skin | 100% | 2131.21 | 1808 / 1809 | 97% | 26.31 | 457 / 472 |
| kidney | 100% | 1206.97 | 89 / 89 | 96% | 13.07 | 866 / 901 |
| uterus | 100% | 1902.62 | 170 / 170 | 96% | 17.65 | 441 / 459 |
| pancreas | 100% | 865.14 | 328 / 328 | 94% | 13.84 | 168 / 178 |
| adrenal gland | 100% | 1767.69 | 258 / 258 | 87% | 9.92 | 201 / 230 |
| liver | 100% | 776.60 | 226 / 226 | 68% | 6.36 | 278 / 406 |
| adipose | 100% | 2132.08 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1632.53 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 24.05 | 29 / 29 |
| spleen | 100% | 2203.78 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.01 | 1 / 1 |
| heart | 99% | 976.85 | 855 / 861 | 0% | 0 | 0 / 0 |
| muscle | 98% | 763.99 | 789 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 19.91 | 43 / 45 |
| peripheral blood | 72% | 1171.41 | 669 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 60% | 4.97 | 48 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0097009 | Biological process | energy homeostasis |
| GO_0045598 | Biological process | regulation of fat cell differentiation |
| GO_0003415 | Biological process | chondrocyte hypertrophy |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0061630 | Molecular function | ubiquitin protein ligase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | MEX3C |
| Protein name | RNA-binding E3 ubiquitin-protein ligase MEX3C (EC 2.3.2.27) (RING finger and KH domain-containing protein 2) (RING finger protein 194) (RING-type E3 ubiquitin transferase MEX3C) Mex-3 RNA binding family member C |
| Synonyms | RKHD2 BM-013 RNF194 |
| Description | FUNCTION: E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation. . |
| Accessions | ENST00000591040.2 A0A6Q8PG18 Q5U5Q3 K7ER23 ENST00000592416.1 ENST00000406189.4 |
