MED29 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051123Biological processRNA polymerase II preinitiation complex assembly
GO_0060261Biological processpositive regulation of transcription initiation by RNA polymerase II
GO_0032968Biological processpositive regulation of transcription elongation by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0016592Cellular componentmediator complex
GO_0005654Cellular componentnucleoplasm
GO_0070847Cellular componentcore mediator complex
GO_0005634Cellular componentnucleus
GO_0008134Molecular functiontranscription factor binding
GO_0005515Molecular functionprotein binding
GO_0003712Molecular functiontranscription coregulator activity

IV. Literature review

[source]
Gene nameMED29
Protein nameMediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)
SynonymsIXL
hCG_43365
DescriptionFUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

AccessionsB4DUA7
ENST00000596297.1
ENST00000315588.11 [Q9NX70-1]
M0R0U2
ENST00000615911.4
M0R3F3
M0R0A0
ENST00000600973.5
ENST00000594368.5 [Q9NX70-2]
ENST00000599417.2
Q9NX70