MED16 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MED16 at tissue level.

III. Associated gene sets

GO_0051123Biological processRNA polymerase II preinitiation complex assembly
GO_0006366Biological processtranscription by RNA polymerase II
GO_0060261Biological processpositive regulation of transcription initiation by RNA polymerase II
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0032968Biological processpositive regulation of transcription elongation by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0016592Cellular componentmediator complex
GO_0005654Cellular componentnucleoplasm
GO_0070847Cellular componentcore mediator complex
GO_0016020Cellular componentmembrane
GO_0005634Cellular componentnucleus
GO_0046966Molecular functionnuclear thyroid hormone receptor binding
GO_0003713Molecular functiontranscription coactivator activity
GO_0042809Molecular functionnuclear vitamin D receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMED16
Protein nameMediator complex subunit 16
Mediator complex subunit MED16 variant MED16_i7
Mediator of RNA polymerase II transcription subunit 16
Mediator complex subunit MED16 variant MED16_i20
Mediator complex subunit MED16 variant MED16_i34
Mediator complex subunit MED16 variant MED16_i23
Mediator complex subunit 16 (Mediator of RNA polymerase II transcription subunit 16)
Mediator complex subunit MED16 variant MED16_i4
Mediator complex subunit MED16 variant MED16_i26
Mediator complex subunit MED16 variant MED16_i31
Mediator complex subunit 16 (Mediator complex subunit MED16 variant MED16_i10)
Mediator complex subunit MED16 variant MED16_i12
Mediator complex subunit MED16 variant MED16_i11
Mediator complex subunit MED16 variant MED16_i25
Mediator complex subunit MED16 variant MED16_i2
Mediator complex subunit MED16 variant MED16_i29
Mediator complex subunit MED16 variant MED16_i33
Mediator complex subunit MED16 variant MED16_i9
Mediator complex subunit MED16 variant MED16_i15
Mediator complex subunit MED16 variant MED16_i17
Mediator complex subunit MED16 variant MED16_i28
Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16)
Mediator complex subunit MED16 variant MED16_i24
Mediator complex subunit MED16 variant MED16_i21
Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92)
Mediator complex subunit MED16 variant MED16_i6
Mediator complex subunit MED16 variant MED16_i30
Mediator complex subunit MED16 variant MED16_i27
Mediator complex subunit MED16 variant MED16_i14
Mediator complex subunit MED16 variant MED16_i16
Mediator complex subunit MED16 variant MED16_i32
Mediator complex subunit MED16 variant MED16_i35
Mediator complex subunit MED16 variant MED16_i13
SynonymsDRIP92
THRAP5
DescriptionFUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. .

AccessionsENST00000592373.1
ENST00000633123.1
B9TWZ8
ENST00000631584.1
B9TWZ5
ENST00000586342.1
B9TX16
ENST00000586017.5
B9TX08
B9TX09
B9TX20
A0A0J9YXK9
B9TX22
B9TX05
ENST00000631914.1
ENST00000631904.1
B9TX00
K7EKX6
B9TX04
A0A0J9YW49
B9TX01
A0A0J9YYC6
B9TWZ9
B9TWZ6
B9TX10
B9TX23
ENST00000631852.1
K7EKX2
B9TX19
B9TX03
ENST00000606828.2
A0A0J9YY02
ENST00000607471.5
U3KQB4
U3KQ43
B9TX12
A0A0J9YXL6
ENST00000632049.1
B9TX02
B9TX26
B9TX11
B9TX28
B9TWZ7
B9TX14
B9TX17
B9TX13
ENST00000606248.5
ENST00000633972.1
A0A087WU12
B9TX18
ENST00000312090.10 [Q9Y2X0-3]
A0A0J9YXE6
A0A0J9YXA0
B9TX21
ENST00000621073.4
B9TX27
ENST00000634211.1
B9TX06
A0A0J9YXE7
Q9Y2X0
ENST00000634212.1
ENST00000395808.7 [Q9Y2X0-2]
K7EKS6
B9TX24
ENST00000325464.6 [Q9Y2X0-1]
B9TX25
B9TX07
B9TX15
ENST00000592943.5