Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 15 studies | 54% ± 24% | |
oligodendrocyte precursor cell | 12 studies | 37% ± 14% | |
glutamatergic neuron | 11 studies | 53% ± 28% | |
GABAergic neuron | 8 studies | 42% ± 23% | |
microglial cell | 7 studies | 25% ± 11% | |
interneuron | 5 studies | 44% ± 23% | |
neuron | 4 studies | 27% ± 8% | |
endothelial cell | 4 studies | 47% ± 20% | |
Mueller cell | 4 studies | 54% ± 16% | |
amacrine cell | 4 studies | 32% ± 12% | |
retina horizontal cell | 4 studies | 38% ± 12% | |
ependymal cell | 3 studies | 50% ± 23% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 28% ± 9% | |
macrophage | 3 studies | 23% ± 0% | |
granule cell | 3 studies | 37% ± 10% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 14 studies | 37% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 352.12 | 2614 / 2642 | 79% | 2.03 | 559 / 705 |
adrenal gland | 100% | 315.68 | 258 / 258 | 15% | 0.26 | 35 / 230 |
thymus | 92% | 98.15 | 602 / 653 | 13% | 0.20 | 79 / 605 |
prostate | 84% | 76.00 | 207 / 245 | 20% | 0.41 | 100 / 502 |
uterus | 91% | 163.87 | 154 / 170 | 6% | 0.13 | 26 / 459 |
lung | 71% | 48.83 | 410 / 578 | 18% | 0.39 | 208 / 1155 |
ovary | 73% | 57.79 | 132 / 180 | 10% | 0.18 | 42 / 430 |
breast | 62% | 46.92 | 284 / 459 | 17% | 0.35 | 189 / 1118 |
spleen | 72% | 50.57 | 174 / 241 | 0% | 0 | 0 / 0 |
bladder | 62% | 59.43 | 13 / 21 | 7% | 0.12 | 33 / 504 |
peripheral blood | 60% | 73.54 | 553 / 929 | 0% | 0 | 0 / 0 |
esophagus | 32% | 17.09 | 458 / 1445 | 25% | 0.53 | 45 / 183 |
muscle | 40% | 46.89 | 320 / 803 | 0% | 0 | 0 / 0 |
heart | 39% | 25.37 | 332 / 861 | 0% | 0 | 0 / 0 |
adipose | 35% | 20.23 | 426 / 1204 | 0% | 0 | 0 / 0 |
intestine | 32% | 17.41 | 309 / 966 | 2% | 0.05 | 13 / 527 |
blood vessel | 32% | 17.71 | 424 / 1335 | 0% | 0 | 0 / 0 |
skin | 29% | 16.66 | 519 / 1809 | 2% | 0.03 | 10 / 472 |
kidney | 26% | 16.78 | 23 / 89 | 1% | 0.02 | 12 / 901 |
stomach | 19% | 11.19 | 68 / 359 | 6% | 0.15 | 18 / 286 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.26 | 5 / 29 |
pancreas | 5% | 2.66 | 18 / 328 | 2% | 0.03 | 4 / 178 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.18 | 2 / 45 |
liver | 3% | 1.26 | 6 / 226 | 0% | 0 | 0 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0016592 | Cellular component | mediator complex |
GO_0008134 | Molecular function | transcription factor binding |
GO_0003713 | Molecular function | transcription coactivator activity |
GO_0005515 | Molecular function | protein binding |
GO_0008013 | Molecular function | beta-catenin binding |
Gene name | MED12L |
Protein name | MED12L protein Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like) Mediator complex subunit 12L |
Synonyms | PRO0314 TRALP TRALPUSH TNRC11L KIAA1635 |
Description | FUNCTION: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). . |
Accessions | ENST00000688234.1 ENST00000422248.6 [Q86YW9-2] H7C4I9 ENST00000309237.8 [Q86YW9-3] Q86YW9 ENST00000480026.1 ENST00000273432.8 B7ZMI1 ENST00000474524.5 [Q86YW9-1] F8WAE6 A0A8I5KW22 ENST00000686666.1 ENST00000687756.1 A0A8I5KY35 A0A8I5KX78 |