Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 15 studies | 42% ± 20% | |
macrophage | 11 studies | 38% ± 18% | |
adipocyte | 10 studies | 46% ± 12% | |
oligodendrocyte precursor cell | 9 studies | 35% ± 17% | |
glutamatergic neuron | 8 studies | 46% ± 28% | |
GABAergic neuron | 6 studies | 43% ± 23% | |
retinal ganglion cell | 5 studies | 43% ± 13% | |
Mueller cell | 5 studies | 39% ± 11% | |
myeloid cell | 5 studies | 25% ± 7% | |
type I pneumocyte | 5 studies | 21% ± 4% | |
endothelial cell | 4 studies | 26% ± 5% | |
type II pneumocyte | 4 studies | 17% ± 2% | |
neuron | 3 studies | 38% ± 15% | |
cardiac muscle cell | 3 studies | 20% ± 1% | |
rod bipolar cell | 3 studies | 30% ± 8% | |
alveolar macrophage | 3 studies | 22% ± 3% | |
club cell | 3 studies | 23% ± 5% | |
oligodendrocyte | 3 studies | 33% ± 16% | |
interneuron | 3 studies | 58% ± 23% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 7283.85 | 258 / 258 | 99% | 57.14 | 228 / 230 |
esophagus | 99% | 2321.13 | 1435 / 1445 | 98% | 70.43 | 179 / 183 |
lung | 97% | 1192.14 | 563 / 578 | 97% | 65.35 | 1115 / 1155 |
intestine | 93% | 1013.99 | 902 / 966 | 93% | 30.97 | 489 / 527 |
bladder | 100% | 2589.81 | 21 / 21 | 79% | 25.42 | 396 / 504 |
stomach | 88% | 1226.67 | 315 / 359 | 88% | 24.49 | 253 / 286 |
brain | 98% | 2074.06 | 2598 / 2642 | 71% | 14.48 | 500 / 705 |
breast | 85% | 1965.97 | 389 / 459 | 77% | 22.22 | 858 / 1118 |
thymus | 94% | 1161.55 | 613 / 653 | 61% | 9.68 | 368 / 605 |
prostate | 91% | 896.68 | 224 / 245 | 62% | 7.92 | 312 / 502 |
skin | 99% | 2132.94 | 1797 / 1809 | 47% | 9.81 | 222 / 472 |
ovary | 100% | 1475.87 | 180 / 180 | 46% | 5.16 | 197 / 430 |
uterus | 74% | 500.10 | 126 / 170 | 71% | 19.07 | 328 / 459 |
liver | 67% | 758.57 | 151 / 226 | 68% | 23.06 | 278 / 406 |
pancreas | 31% | 181.69 | 102 / 328 | 78% | 11.77 | 138 / 178 |
kidney | 43% | 275.88 | 38 / 89 | 61% | 10.85 | 551 / 901 |
muscle | 100% | 3169.00 | 803 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 1682.70 | 1327 / 1335 | 0% | 0 | 0 / 0 |
adipose | 99% | 2808.57 | 1189 / 1204 | 0% | 0 | 0 / 0 |
spleen | 89% | 867.85 | 214 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 87% | 20.50 | 39 / 45 |
heart | 86% | 1650.03 | 743 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 41% | 4.19 | 12 / 29 |
eye | 0% | 0 | 0 / 0 | 28% | 3.94 | 22 / 80 |
peripheral blood | 22% | 217.71 | 200 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1902031 | Biological process | regulation of NADP metabolic process |
GO_0006739 | Biological process | NADP metabolic process |
GO_0006734 | Biological process | NADH metabolic process |
GO_0006090 | Biological process | pyruvate metabolic process |
GO_0005975 | Biological process | carbohydrate metabolic process |
GO_0009165 | Biological process | nucleotide biosynthetic process |
GO_0009725 | Biological process | response to hormone |
GO_0009743 | Biological process | response to carbohydrate |
GO_0006108 | Biological process | malate metabolic process |
GO_0051289 | Biological process | protein homotetramerization |
GO_0005739 | Cellular component | mitochondrion |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004470 | Molecular function | malic enzyme activity |
GO_0043531 | Molecular function | ADP binding |
GO_0009055 | Molecular function | electron transfer activity |
GO_0051287 | Molecular function | NAD binding |
GO_0004473 | Molecular function | malate dehydrogenase (decarboxylating) (NADP+) activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0030145 | Molecular function | manganese ion binding |
GO_0050661 | Molecular function | NADP binding |
GO_0008948 | Molecular function | oxaloacetate decarboxylase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ME1 |
Protein name | Cadherin NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1) |
Synonyms | |
Description | FUNCTION: Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate. . |
Accessions | P48163 ENST00000369705.4 [P48163-1] O15199 |