Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 11 studies | 27% ± 11% | |
endothelial cell | 10 studies | 31% ± 15% | |
glutamatergic neuron | 10 studies | 41% ± 27% | |
astrocyte | 10 studies | 32% ± 16% | |
GABAergic neuron | 9 studies | 39% ± 25% | |
oligodendrocyte precursor cell | 8 studies | 26% ± 11% | |
plasmacytoid dendritic cell | 8 studies | 21% ± 5% | |
interneuron | 6 studies | 44% ± 27% | |
fibroblast | 6 studies | 24% ± 9% | |
ciliated cell | 6 studies | 22% ± 5% | |
macrophage | 5 studies | 24% ± 6% | |
microglial cell | 5 studies | 24% ± 6% | |
epithelial cell | 5 studies | 31% ± 16% | |
adipocyte | 5 studies | 22% ± 3% | |
neuron | 4 studies | 29% ± 11% | |
granule cell | 4 studies | 21% ± 3% | |
cardiac muscle cell | 4 studies | 19% ± 1% | |
basal cell | 4 studies | 30% ± 19% | |
club cell | 4 studies | 21% ± 7% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 7% | |
GABAergic interneuron | 3 studies | 26% ± 4% | |
hepatocyte | 3 studies | 57% ± 20% | |
pericyte | 3 studies | 24% ± 7% | |
smooth muscle cell | 3 studies | 18% ± 1% | |
type I pneumocyte | 3 studies | 21% ± 7% | |
lymphocyte | 3 studies | 25% ± 6% | |
goblet cell | 3 studies | 25% ± 12% | |
transit amplifying cell | 3 studies | 40% ± 25% | |
erythroblast | 3 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4438.23 | 1445 / 1445 | 100% | 15.84 | 183 / 183 |
intestine | 100% | 4579.00 | 966 / 966 | 99% | 10.77 | 524 / 527 |
thymus | 100% | 6826.07 | 653 / 653 | 99% | 12.09 | 600 / 605 |
breast | 100% | 4764.11 | 459 / 459 | 99% | 12.79 | 1108 / 1118 |
skin | 100% | 6972.94 | 1809 / 1809 | 99% | 12.46 | 466 / 472 |
brain | 99% | 5295.95 | 2627 / 2642 | 99% | 12.96 | 699 / 705 |
bladder | 100% | 4526.71 | 21 / 21 | 98% | 8.64 | 496 / 504 |
prostate | 100% | 4164.63 | 245 / 245 | 98% | 9.67 | 494 / 502 |
lung | 100% | 4303.80 | 577 / 578 | 99% | 10.06 | 1138 / 1155 |
stomach | 100% | 3760.53 | 359 / 359 | 98% | 11.62 | 281 / 286 |
uterus | 100% | 5988.46 | 170 / 170 | 98% | 9.21 | 449 / 459 |
pancreas | 99% | 3365.45 | 326 / 328 | 98% | 7.51 | 175 / 178 |
kidney | 100% | 3141.16 | 89 / 89 | 94% | 7.15 | 847 / 901 |
ovary | 100% | 7502.42 | 180 / 180 | 94% | 6.37 | 404 / 430 |
adrenal gland | 100% | 4576.66 | 258 / 258 | 93% | 7.05 | 214 / 230 |
liver | 100% | 5042.12 | 226 / 226 | 87% | 4.94 | 355 / 406 |
adipose | 100% | 4315.76 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 4722.52 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4861.45 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.25 | 1 / 1 |
blood vessel | 100% | 4139.86 | 1332 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 9.46 | 78 / 80 |
lymph node | 0% | 0 | 0 / 0 | 97% | 9.68 | 28 / 29 |
heart | 96% | 3266.64 | 829 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 9.17 | 43 / 45 |
peripheral blood | 40% | 2373.32 | 369 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000027 | Biological process | ribosomal large subunit assembly |
GO_0000055 | Biological process | ribosomal large subunit export from nucleus |
GO_0045111 | Cellular component | intermediate filament cytoskeleton |
GO_0030687 | Cellular component | preribosome, large subunit precursor |
GO_0005730 | Cellular component | nucleolus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0016020 | Cellular component | membrane |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | MDN1 |
Protein name | MDN1 protein Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein) |
Synonyms | KIAA0301 |
Description | FUNCTION: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits . Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus (By similarity). At an early stage in 60S maturation, mediates the dissociation of the PeBoW complex (PES1-BOP1-WDR12) from early pre-60S particles, rendering them competent for export from the nucleolus to the nucleoplasm (By similarity). Subsequently recruited to the nucleoplasmic particles through interaction with SUMO-conjugated PELP1 complex . This binding is only possible if the 5S RNP at the central protuberance has undergone the rotation to complete its maturation (By similarity). . |
Accessions | Q6PJJ1 ENST00000369393.8 Q9NU22 |