MCMBP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007062Biological processsister chromatid cohesion
GO_0051301Biological processcell division
GO_0006261Biological processDNA-templated DNA replication
GO_0042555Cellular componentMCM complex
GO_0030054Cellular componentcell junction
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene nameMCMBP
Protein nameMini-chromosome maintenance complex-binding protein
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)
SynonymsC10orf119
hCG_40606
DescriptionFUNCTION: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. .

AccessionsENST00000360003.7 [Q9BTE3-1]
ENST00000369077.4 [Q9BTE3-2]
Q9BTE3
A0A0S2Z614
A0A0S2Z5P5