Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 25% ± 10% | |
microglial cell | 6 studies | 26% ± 9% | |
GABAergic neuron | 6 studies | 29% ± 14% | |
macrophage | 6 studies | 24% ± 5% | |
epithelial cell | 5 studies | 24% ± 7% | |
astrocyte | 5 studies | 26% ± 9% | |
glutamatergic neuron | 4 studies | 38% ± 15% | |
oligodendrocyte | 4 studies | 24% ± 6% | |
ciliated cell | 3 studies | 18% ± 2% | |
myeloid cell | 3 studies | 18% ± 3% | |
oligodendrocyte precursor cell | 3 studies | 32% ± 8% | |
endothelial cell of lymphatic vessel | 3 studies | 19% ± 4% | |
fibroblast | 3 studies | 19% ± 5% | |
adipocyte | 3 studies | 17% ± 2% | |
interneuron | 3 studies | 37% ± 22% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 7 studies | 30% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4196.34 | 1445 / 1445 | 100% | 22.16 | 183 / 183 |
stomach | 100% | 3682.04 | 359 / 359 | 99% | 17.57 | 284 / 286 |
intestine | 100% | 4740.04 | 966 / 966 | 99% | 17.03 | 520 / 527 |
lung | 100% | 4687.76 | 578 / 578 | 98% | 16.14 | 1133 / 1155 |
breast | 100% | 5155.97 | 459 / 459 | 98% | 24.53 | 1095 / 1118 |
skin | 100% | 5218.36 | 1809 / 1809 | 98% | 23.94 | 461 / 472 |
brain | 99% | 3147.82 | 2621 / 2642 | 98% | 21.41 | 693 / 705 |
prostate | 100% | 4676.17 | 245 / 245 | 96% | 18.00 | 484 / 502 |
pancreas | 100% | 2679.27 | 327 / 328 | 97% | 13.50 | 172 / 178 |
bladder | 100% | 4395.48 | 21 / 21 | 96% | 13.86 | 485 / 504 |
thymus | 100% | 5318.22 | 653 / 653 | 93% | 13.52 | 564 / 605 |
kidney | 100% | 3273.11 | 89 / 89 | 93% | 13.56 | 835 / 901 |
uterus | 100% | 5475.26 | 170 / 170 | 93% | 13.73 | 425 / 459 |
ovary | 100% | 5058.19 | 180 / 180 | 91% | 12.05 | 392 / 430 |
adrenal gland | 100% | 3758.55 | 258 / 258 | 84% | 8.65 | 193 / 230 |
liver | 100% | 2070.12 | 225 / 226 | 78% | 7.17 | 317 / 406 |
adipose | 100% | 4794.10 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 5948.65 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5575.99 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4187.60 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 2900.90 | 847 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 14.32 | 78 / 80 |
tonsil | 0% | 0 | 0 / 0 | 96% | 14.62 | 43 / 45 |
peripheral blood | 95% | 3180.76 | 882 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 17.51 | 27 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006406 | Biological process | mRNA export from nucleus |
GO_0015031 | Biological process | protein transport |
GO_0016446 | Biological process | somatic hypermutation of immunoglobulin genes |
GO_0034728 | Biological process | nucleosome organization |
GO_0016973 | Biological process | poly(A)+ mRNA export from nucleus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0070390 | Cellular component | transcription export complex 2 |
GO_0044615 | Cellular component | nuclear pore nuclear basket |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005694 | Cellular component | chromosome |
GO_0031965 | Cellular component | nuclear membrane |
GO_0005634 | Cellular component | nucleus |
GO_0042393 | Molecular function | histone binding |
GO_0003676 | Molecular function | nucleic acid binding |
GO_0003682 | Molecular function | chromatin binding |
GO_0010484 | Molecular function | histone H3 acetyltransferase activity |
GO_0004402 | Molecular function | histone acetyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | MCM3AP |
Protein name | Germinal-center associated nuclear protein (GANP) (EC 2.3.1.48) (80 kDa MCM3-associated protein) (MCM3 acetylating protein) (MCM3AP) (EC 2.3.1.-) (MCM3 acetyltransferase) Alternative protein MCM3AP Minichromosome maintenance complex component 3 associated protein |
Synonyms | KIAA0572 GANP MAP80 |
Description | FUNCTION: [Isoform GANP]: As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores . Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations . .; FUNCTION: [Isoform MCM3AP]: Binds to and acetylates the replication protein MCM3. Plays a role in the initiation of DNA replication and participates in controls that ensure that DNA replication initiates only once per cell cycle . Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations . . |
Accessions | O60318 A0A0A0MSZ7 ENST00000291688.6 [O60318-1] L8ECA8 ENST00000397708.1 [O60318-1] ENST00000426537.1 |