Insufficient scRNA-seq data for expression of MC3R at single-cell level.
Insufficient scRNA-seq data for expression of MC3R at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 24% | 7.34 | 630 / 2642 | 1% | 0.01 | 5 / 705 |
adrenal gland | 13% | 0.39 | 34 / 258 | 5% | 0.98 | 12 / 230 |
bladder | 10% | 0.29 | 2 / 21 | 1% | 0.01 | 4 / 504 |
skin | 4% | 0.10 | 64 / 1809 | 3% | 0.09 | 15 / 472 |
muscle | 5% | 0.12 | 40 / 803 | 0% | 0 | 0 / 0 |
intestine | 3% | 0.07 | 25 / 966 | 2% | 0.06 | 10 / 527 |
kidney | 3% | 0.07 | 3 / 89 | 1% | 0.02 | 9 / 901 |
stomach | 2% | 0.05 | 8 / 359 | 2% | 0.04 | 6 / 286 |
pancreas | 4% | 0.11 | 14 / 328 | 0% | 0 | 0 / 178 |
lung | 1% | 0.08 | 8 / 578 | 3% | 0.10 | 30 / 1155 |
uterus | 2% | 0.07 | 3 / 170 | 1% | 0.02 | 4 / 459 |
ovary | 2% | 0.04 | 4 / 180 | 0% | 0.07 | 1 / 430 |
prostate | 2% | 0.06 | 6 / 245 | 0% | 0 | 0 / 502 |
esophagus | 2% | 0.07 | 32 / 1445 | 0% | 0 | 0 / 183 |
breast | 2% | 0.05 | 8 / 459 | 0% | 0.02 | 5 / 1118 |
liver | 1% | 0.03 | 3 / 226 | 0% | 0.01 | 1 / 406 |
peripheral blood | 2% | 0.04 | 14 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 0.04 | 19 / 1335 | 0% | 0 | 0 / 0 |
heart | 1% | 0.03 | 12 / 861 | 0% | 0 | 0 / 0 |
spleen | 1% | 0.03 | 3 / 241 | 0% | 0 | 0 / 0 |
thymus | 1% | 0.02 | 6 / 653 | 0% | 0.02 | 1 / 605 |
adipose | 1% | 0.02 | 9 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008217 | Biological process | regulation of blood pressure |
GO_0055078 | Biological process | sodium ion homeostasis |
GO_0032922 | Biological process | circadian regulation of gene expression |
GO_0060259 | Biological process | regulation of feeding behavior |
GO_0002027 | Biological process | regulation of heart rate |
GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
GO_0042309 | Biological process | homoiothermy |
GO_0019222 | Biological process | regulation of metabolic process |
GO_0045475 | Biological process | locomotor rhythm |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0042923 | Molecular function | neuropeptide binding |
GO_0004977 | Molecular function | melanocortin receptor activity |
GO_0017046 | Molecular function | peptide hormone binding |
GO_0004980 | Molecular function | melanocyte-stimulating hormone receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | MC3R |
Protein name | Melanocortin receptor 3 (MC3-R) |
Synonyms | |
Description | FUNCTION: Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. . |
Accessions | P41968 ENST00000243911.2 |