Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 19 studies | 28% ± 8% | |
plasmacytoid dendritic cell | 15 studies | 51% ± 15% | |
classical monocyte | 14 studies | 30% ± 7% | |
non-classical monocyte | 14 studies | 29% ± 11% | |
conventional dendritic cell | 13 studies | 35% ± 12% | |
monocyte | 8 studies | 21% ± 4% | |
dendritic cell | 8 studies | 44% ± 4% | |
memory B cell | 8 studies | 18% ± 3% | |
naive B cell | 7 studies | 19% ± 3% | |
B cell | 7 studies | 20% ± 3% | |
myeloid cell | 5 studies | 26% ± 9% | |
alveolar macrophage | 5 studies | 20% ± 3% | |
microglial cell | 4 studies | 21% ± 4% | |
common myeloid progenitor | 3 studies | 25% ± 4% | |
precursor B cell | 3 studies | 25% ± 1% | |
immature B cell | 3 studies | 21% ± 4% | |
plasmablast | 3 studies | 37% ± 20% | |
regulatory T cell | 3 studies | 17% ± 1% | |
intermediate monocyte | 3 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4172.34 | 1445 / 1445 | 100% | 43.30 | 183 / 183 |
lung | 100% | 7333.63 | 578 / 578 | 100% | 52.52 | 1155 / 1155 |
skin | 100% | 5188.32 | 1809 / 1809 | 100% | 93.29 | 472 / 472 |
stomach | 100% | 4749.90 | 359 / 359 | 100% | 42.16 | 285 / 286 |
prostate | 100% | 4906.92 | 245 / 245 | 100% | 46.61 | 500 / 502 |
breast | 100% | 5020.90 | 459 / 459 | 100% | 47.99 | 1113 / 1118 |
pancreas | 100% | 3718.80 | 328 / 328 | 99% | 45.19 | 177 / 178 |
kidney | 100% | 3545.13 | 89 / 89 | 99% | 40.63 | 891 / 901 |
intestine | 100% | 5452.26 | 966 / 966 | 99% | 38.40 | 521 / 527 |
ovary | 100% | 3514.66 | 180 / 180 | 99% | 45.52 | 425 / 430 |
bladder | 100% | 4619.14 | 21 / 21 | 98% | 40.09 | 496 / 504 |
uterus | 100% | 3953.99 | 170 / 170 | 98% | 40.30 | 451 / 459 |
thymus | 100% | 4009.24 | 652 / 653 | 98% | 28.93 | 594 / 605 |
liver | 99% | 2339.44 | 223 / 226 | 95% | 31.46 | 386 / 406 |
adrenal gland | 100% | 4388.25 | 258 / 258 | 87% | 18.78 | 199 / 230 |
brain | 71% | 971.93 | 1873 / 2642 | 98% | 29.90 | 688 / 705 |
adipose | 100% | 6324.46 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 92.59 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 96.59 | 29 / 29 |
spleen | 100% | 12549.59 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 53.70 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.16 | 1 / 1 |
blood vessel | 100% | 4630.81 | 1333 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 9817.12 | 926 / 929 | 0% | 0 | 0 / 0 |
heart | 94% | 2019.43 | 813 / 861 | 0% | 0 | 0 / 0 |
muscle | 81% | 1286.58 | 650 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006517 | Biological process | protein deglycosylation |
GO_0009313 | Biological process | oligosaccharide catabolic process |
GO_0036211 | Biological process | protein modification process |
GO_0007611 | Biological process | learning or memory |
GO_0006013 | Biological process | mannose metabolic process |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0035578 | Cellular component | azurophil granule lumen |
GO_0005615 | Cellular component | extracellular space |
GO_0043202 | Cellular component | lysosomal lumen |
GO_0005764 | Cellular component | lysosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005576 | Cellular component | extracellular region |
GO_0004559 | Molecular function | alpha-mannosidase activity |
GO_0030246 | Molecular function | carbohydrate binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | MAN2B1 |
Protein name | alpha-mannosidase (EC 3.2.1.24) Mannosidase alpha class 2B member 1 Lysosomal alpha-mannosidase (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) [Cleaved into: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha-mannosidase E peptide] |
Synonyms | MANB LAMAN |
Description | FUNCTION: Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover. Cleaves all known types of alpha-mannosidic linkages. |
Accessions | ENST00000486847.2 M0QZG6 M0QXY0 M0QYZ1 ENST00000593686.1 M0R174 ENST00000456935.7 [O00754-1] ENST00000598876.1 ENST00000221363.8 [O00754-2] ENST00000596591.1 O00754 |