Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 3 studies | 21% ± 5% |
Insufficient scRNA-seq data for expression of MACIR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1751.44 | 2642 / 2642 | 100% | 23.83 | 703 / 705 |
breast | 100% | 952.27 | 457 / 459 | 98% | 44.72 | 1101 / 1118 |
skin | 98% | 657.43 | 1774 / 1809 | 97% | 23.63 | 459 / 472 |
intestine | 96% | 1149.49 | 926 / 966 | 98% | 22.38 | 517 / 527 |
esophagus | 98% | 600.45 | 1415 / 1445 | 95% | 13.08 | 174 / 183 |
prostate | 95% | 496.56 | 232 / 245 | 97% | 27.58 | 489 / 502 |
stomach | 93% | 763.94 | 335 / 359 | 97% | 20.39 | 278 / 286 |
thymus | 99% | 573.81 | 648 / 653 | 90% | 9.41 | 544 / 605 |
pancreas | 90% | 363.55 | 294 / 328 | 97% | 15.49 | 172 / 178 |
ovary | 88% | 370.68 | 158 / 180 | 97% | 16.40 | 419 / 430 |
uterus | 85% | 293.83 | 145 / 170 | 94% | 13.54 | 433 / 459 |
kidney | 99% | 494.82 | 88 / 89 | 81% | 10.13 | 727 / 901 |
lung | 86% | 368.14 | 499 / 578 | 92% | 11.79 | 1066 / 1155 |
bladder | 86% | 308.43 | 18 / 21 | 87% | 12.77 | 439 / 504 |
adrenal gland | 95% | 477.41 | 245 / 258 | 76% | 9.28 | 175 / 230 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.12 | 1 / 1 |
adipose | 99% | 1036.16 | 1192 / 1204 | 0% | 0 | 0 / 0 |
spleen | 97% | 575.27 | 234 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 11.35 | 40 / 45 |
muscle | 83% | 654.62 | 669 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 80% | 295.37 | 1073 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 72% | 9.10 | 21 / 29 |
eye | 0% | 0 | 0 / 0 | 69% | 6.13 | 55 / 80 |
heart | 62% | 199.95 | 536 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 59% | 863.23 | 550 / 929 | 0% | 0 | 0 / 0 |
liver | 2% | 5.97 | 5 / 226 | 31% | 3.97 | 127 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010761 | Biological process | fibroblast migration |
GO_0060271 | Biological process | cilium assembly |
GO_0015031 | Biological process | protein transport |
GO_0010633 | Biological process | negative regulation of epithelial cell migration |
GO_1900016 | Biological process | negative regulation of cytokine production involved in inflammatory response |
GO_0050728 | Biological process | negative regulation of inflammatory response |
GO_0006954 | Biological process | inflammatory response |
GO_0010764 | Biological process | negative regulation of fibroblast migration |
GO_0010631 | Biological process | epithelial cell migration |
GO_0035869 | Cellular component | ciliary transition zone |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | MACIR |
Protein name | Macrophage immunometabolism regulator |
Synonyms | C5orf30 |
Description | FUNCTION: Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages . The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis . May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B . May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells . . |
Accessions | ENST00000515669.5 ENST00000319933.7 ENST00000510890.1 Q96GV9 |