LY6H report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0095500Biological processacetylcholine receptor signaling pathway
GO_0007399Biological processnervous system development
GO_0009887Biological processanimal organ morphogenesis
GO_0098552Cellular componentside of membrane
GO_0045202Cellular componentsynapse
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0033130Molecular functionacetylcholine receptor binding
GO_0005515Molecular functionprotein binding
GO_0030550Molecular functionacetylcholine receptor inhibitor activity

IV. Literature review

[source]
Gene nameLY6H
Protein nameLymphocyte antigen 6H (Ly-6H)
Synonyms
DescriptionFUNCTION: Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons. .

AccessionsENST00000342752.9 [O94772-2]
ENST00000631670.1 [O94772-2]
ENST00000430474.6 [O94772-1]
O94772
ENST00000610554.2 [O94772-1]
ENST00000615434.4 [O94772-2]
ENST00000615409.1 [O94772-1]
ENST00000414417.6 [O94772-2]