LPAR4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LPAR4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LPAR4 at tissue level.

III. Associated gene sets

GO_0035025Biological processpositive regulation of Rho protein signal transduction
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0016604Cellular componentnuclear body
GO_0005886Cellular componentplasma membrane
GO_0035727Molecular functionlysophosphatidic acid binding
GO_0070915Molecular functionlysophosphatidic acid receptor activity

IV. Literature review

[source]
Gene nameLPAR4
Protein nameLysophosphatidic acid receptor 4
Lysophosphatidic acid receptor 4 (LPA receptor 4) (LPA-4) (G-protein coupled receptor 23) (P2Y purinoceptor 9) (P2Y9) (P2Y5-like receptor) (Purinergic receptor 9)
SynonymsGPR23
P2RY9
LPA4
DescriptionFUNCTION: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA. .

AccessionsENST00000514744.5
Q99677
ENST00000614823.5
ENST00000435339.3
V9GY74