Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreatic A cell | 3 studies | 45% ± 25% | |
| basal cell | 3 studies | 25% ± 6% |
Insufficient scRNA-seq data for expression of LOXL4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1236.18 | 245 / 245 | 95% | 18.07 | 476 / 502 |
| pancreas | 96% | 681.96 | 315 / 328 | 92% | 34.19 | 163 / 178 |
| thymus | 100% | 1356.68 | 651 / 653 | 85% | 21.10 | 517 / 605 |
| ovary | 100% | 1218.26 | 180 / 180 | 77% | 14.02 | 331 / 430 |
| lung | 99% | 794.28 | 574 / 578 | 71% | 19.68 | 820 / 1155 |
| kidney | 93% | 782.52 | 83 / 89 | 75% | 10.47 | 674 / 901 |
| skin | 93% | 1230.09 | 1681 / 1809 | 72% | 169.52 | 341 / 472 |
| uterus | 100% | 1415.57 | 170 / 170 | 58% | 16.29 | 267 / 459 |
| breast | 100% | 1671.17 | 458 / 459 | 42% | 8.41 | 473 / 1118 |
| bladder | 100% | 895.14 | 21 / 21 | 40% | 9.26 | 202 / 504 |
| esophagus | 81% | 781.82 | 1171 / 1445 | 45% | 15.07 | 83 / 183 |
| intestine | 92% | 1161.89 | 891 / 966 | 14% | 2.65 | 76 / 527 |
| liver | 38% | 546.70 | 86 / 226 | 68% | 30.74 | 277 / 406 |
| adrenal gland | 85% | 400.76 | 219 / 258 | 20% | 3.81 | 46 / 230 |
| blood vessel | 99% | 1349.31 | 1325 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 99% | 1108.57 | 1192 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 91% | 463.29 | 219 / 241 | 0% | 0 | 0 / 0 |
| muscle | 89% | 857.44 | 718 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 85% | 35.95 | 68 / 80 |
| stomach | 55% | 410.74 | 198 / 359 | 16% | 1.92 | 46 / 286 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 20.18 | 24 / 45 |
| heart | 37% | 206.93 | 318 / 861 | 0% | 0 | 0 / 0 |
| brain | 4% | 15.48 | 105 / 2642 | 10% | 1.25 | 71 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.52 | 3 / 29 |
| peripheral blood | 0% | 0.65 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0030199 | Biological process | collagen fibril organization |
| GO_0018057 | Biological process | peptidyl-lysine oxidation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0043235 | Cellular component | receptor complex |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0016020 | Cellular component | membrane |
| GO_0004720 | Molecular function | protein-lysine 6-oxidase activity |
| GO_0005507 | Molecular function | copper ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LOXL4 |
| Protein name | Lysyl oxidase homolog 4 (EC 1.4.3.13) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C) |
| Synonyms | LOXC |
| Description | FUNCTION: Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers. . |
| Accessions | Q96JB6 ENST00000260702.4 |