LMX1B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LMX1B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LMX1B at tissue level.

III. Associated gene sets

GO_0030182Biological processneuron differentiation
GO_0071542Biological processdopaminergic neuron differentiation
GO_0006355Biological processregulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0009953Biological processdorsal/ventral pattern formation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameLMX1B
Protein nameLIM homeobox transcription factor 1-beta (LIM/homeobox protein 1.2) (LMX-1.2) (LIM/homeobox protein LMX1B)
LIM homeobox transcription factor 1 beta isoform 2
LIM homeobox transcription factor 1 beta isoform 1
LMX1B protein
Synonyms
DescriptionFUNCTION: Transcription factor involved in the regulation of podocyte-expressed genes . Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. .

AccessionsA0A0S2Z439
ENST00000355497.10 [O60663-3]
Q6ISE0
A0A0S2Z4L1
O60663
B7ZLH2
ENST00000526117.6 [O60663-2]
ENST00000373474.9 [O60663-1]