Insufficient scRNA-seq data for expression of LMX1A at single-cell level.
Insufficient scRNA-seq data for expression of LMX1A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adipose | 80% | 79.37 | 967 / 1204 | 0% | 0 | 0 / 0 |
breast | 73% | 44.66 | 336 / 459 | 2% | 0.08 | 27 / 1118 |
esophagus | 71% | 43.94 | 1019 / 1445 | 3% | 0.10 | 6 / 183 |
bladder | 67% | 30.90 | 14 / 21 | 1% | 0.03 | 7 / 504 |
intestine | 63% | 20.03 | 606 / 966 | 4% | 0.28 | 19 / 527 |
thymus | 50% | 17.10 | 325 / 653 | 0% | 0 | 0 / 605 |
muscle | 47% | 11.26 | 380 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 41% | 13.11 | 547 / 1335 | 0% | 0 | 0 / 0 |
uterus | 29% | 15.09 | 50 / 170 | 9% | 0.45 | 40 / 459 |
skin | 35% | 11.65 | 627 / 1809 | 0% | 0.01 | 2 / 472 |
stomach | 31% | 9.34 | 113 / 359 | 3% | 0.10 | 10 / 286 |
brain | 19% | 14.36 | 515 / 2642 | 11% | 0.38 | 76 / 705 |
heart | 23% | 6.33 | 198 / 861 | 0% | 0 | 0 / 0 |
lung | 18% | 5.07 | 103 / 578 | 4% | 0.15 | 45 / 1155 |
liver | 15% | 2.99 | 35 / 226 | 2% | 0.07 | 7 / 406 |
prostate | 7% | 2.33 | 18 / 245 | 0% | 0 | 0 / 502 |
ovary | 2% | 0.77 | 3 / 180 | 4% | 0.12 | 17 / 430 |
adrenal gland | 1% | 1.90 | 2 / 258 | 3% | 0.28 | 8 / 230 |
pancreas | 0% | 0.04 | 1 / 328 | 1% | 0.02 | 1 / 178 |
kidney | 0% | 0 | 0 / 89 | 0% | 0.04 | 2 / 901 |
peripheral blood | 0% | 0.01 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001558 | Biological process | regulation of cell growth |
GO_1904948 | Biological process | midbrain dopaminergic neuron differentiation |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0021542 | Biological process | dentate gyrus development |
GO_0021953 | Biological process | central nervous system neuron differentiation |
GO_0071542 | Biological process | dopaminergic neuron differentiation |
GO_0030182 | Biological process | neuron differentiation |
GO_0045665 | Biological process | negative regulation of neuron differentiation |
GO_0042048 | Biological process | olfactory behavior |
GO_0021549 | Biological process | cerebellum development |
GO_0007613 | Biological process | memory |
GO_0050808 | Biological process | synapse organization |
GO_0007626 | Biological process | locomotory behavior |
GO_0007411 | Biological process | axon guidance |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | LMX1A |
Protein name | LIM homeobox transcription factor 1-alpha (LIM/homeobox protein 1.1) (LMX-1.1) (LIM/homeobox protein LMX1A) LIM homeobox transcription factor 1, alpha |
Synonyms | hCG_21707 |
Description | FUNCTION: Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). . |
Accessions | ENST00000294816.6 [Q8TE12-1] ENST00000342310.7 [Q8TE12-1] ENST00000367893.4 [Q8TE12-1] Q8TE12 Q6NZ39 |