Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| natural killer cell | 4 studies | 26% ± 9% | |
| epithelial cell | 3 studies | 20% ± 4% | |
| transit amplifying cell | 3 studies | 37% ± 9% | |
| CD8-positive, alpha-beta T cell | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 24% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 2580.17 | 1806 / 1809 | 100% | 31.20 | 472 / 472 |
| bladder | 100% | 1181.95 | 21 / 21 | 100% | 25.95 | 503 / 504 |
| uterus | 100% | 2013.55 | 170 / 170 | 100% | 40.93 | 458 / 459 |
| thymus | 100% | 2953.76 | 653 / 653 | 99% | 19.54 | 597 / 605 |
| ovary | 100% | 2142.06 | 180 / 180 | 98% | 16.62 | 423 / 430 |
| lung | 99% | 1529.12 | 575 / 578 | 98% | 17.76 | 1137 / 1155 |
| breast | 98% | 1509.91 | 452 / 459 | 99% | 21.13 | 1111 / 1118 |
| intestine | 99% | 1523.31 | 956 / 966 | 99% | 23.93 | 521 / 527 |
| pancreas | 99% | 1503.60 | 326 / 328 | 98% | 13.33 | 175 / 178 |
| stomach | 99% | 1137.86 | 355 / 359 | 98% | 21.63 | 281 / 286 |
| prostate | 100% | 2167.74 | 245 / 245 | 97% | 9.74 | 485 / 502 |
| brain | 96% | 1035.98 | 2528 / 2642 | 98% | 13.81 | 692 / 705 |
| esophagus | 94% | 1123.31 | 1354 / 1445 | 100% | 17.91 | 183 / 183 |
| kidney | 99% | 1232.75 | 88 / 89 | 92% | 11.59 | 831 / 901 |
| adrenal gland | 100% | 1107.80 | 258 / 258 | 88% | 9.29 | 203 / 230 |
| liver | 96% | 858.03 | 217 / 226 | 90% | 12.09 | 365 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 27.20 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 38.91 | 29 / 29 |
| spleen | 100% | 2738.47 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 47.01 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.18 | 1 / 1 |
| adipose | 97% | 899.98 | 1168 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 97% | 777.58 | 1293 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 90% | 2187.74 | 835 / 929 | 0% | 0 | 0 / 0 |
| heart | 57% | 297.78 | 494 / 861 | 0% | 0 | 0 / 0 |
| muscle | 50% | 233.47 | 401 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006281 | Biological process | DNA repair |
| GO_0006287 | Biological process | base-excision repair, gap-filling |
| GO_0006273 | Biological process | lagging strand elongation |
| GO_0033151 | Biological process | V(D)J recombination |
| GO_0051301 | Biological process | cell division |
| GO_1903461 | Biological process | Okazaki fragment processing involved in mitotic DNA replication |
| GO_0071897 | Biological process | DNA biosynthetic process |
| GO_0009653 | Biological process | anatomical structure morphogenesis |
| GO_0006284 | Biological process | base-excision repair |
| GO_0006298 | Biological process | mismatch repair |
| GO_0006266 | Biological process | DNA ligation |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003910 | Molecular function | DNA ligase (ATP) activity |
| GO_0003909 | Molecular function | DNA ligase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LIG1 |
| Protein name | DNA ligase (EC 6.5.1.1) DNA ligase 1 DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1) Ligase I, DNA, ATP-dependent |
| Synonyms | hCG_15029 |
| Description | FUNCTION: DNA ligase that seals nicks in double-stranded during DNA repair . Also involved in DNA replication and DNA recombination. . |
| Accessions | B4E135 P18858 ENST00000699868.1 [P18858-1] A0A8V8TQC8 Q76GR4 ENST00000542460.5 ENST00000699878.1 ENST00000427526.6 [P18858-3] ENST00000594759.5 ENST00000699871.1 A0A8V8TPA5 F5GZ28 A0A8V8TQQ7 ENST00000596672.6 ENST00000699875.1 ENST00000699877.1 A0A8V8TQQ3 M0R0Q7 ENST00000699866.1 A0A8V8TPB0 ENST00000699869.1 ENST00000601091.5 [P18858-2] A0A8V8TPH8 ENST00000699874.1 ENST00000699872.1 M0R254 A0A8V8TP03 A0A8V8TPH4 ENST00000263274.12 [P18858-1] A0A8V8TQC4 A0A8V8TNZ9 ENST00000699873.1 ENST00000699870.1 ENST00000596549.6 |
