LHX6 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LHX6 at tissue level.

III. Associated gene sets

GO_0030182Biological processneuron differentiation
GO_0021884Biological processforebrain neuron development
GO_0021800Biological processcerebral cortex tangential migration
GO_0048469Biological processcell maturation
GO_0021853Biological processcerebral cortex GABAergic interneuron migration
GO_0021799Biological processcerebral cortex radially oriented cell migration
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameLHX6
Protein nameLIM/homeobox protein Lhx6 (LIM homeobox protein 6) (LIM/homeobox protein Lhx6.1)
LIM homeobox 6
SynonymsLHX6.1
DescriptionFUNCTION: Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity). .

AccessionsENST00000541397.2 [Q9UPM6-5]
ENST00000340587.7 [Q9UPM6-4]
ENST00000560485.1
H0YKH7
ENST00000373754.6 [Q9UPM6-2]
ENST00000394319.9 [Q9UPM6-3]
ENST00000559895.5 [Q9UPM6-6]
ENST00000373755.6 [Q9UPM6-1]
H0YMY8
ENST00000482062.1
Q9UPM6
Q3SY65
ENST00000464484.3
H0YMH3