LHX5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of LHX5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LHX5 at tissue level.

III. Associated gene sets

GO_1902692Biological processregulation of neuroblast proliferation
GO_0030182Biological processneuron differentiation
GO_0021766Biological processhippocampus development
GO_0021527Biological processspinal cord association neuron differentiation
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0007405Biological processneuroblast proliferation
GO_0021702Biological processcerebellar Purkinje cell differentiation
GO_0021846Biological processcell proliferation in forebrain
GO_0021937Biological processcerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
GO_0021879Biological processforebrain neuron differentiation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameLHX5
Protein nameLIM/homeobox protein Lhx5 (LIM homeobox protein 5)
Synonyms
DescriptionFUNCTION: Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.

AccessionsENST00000261731.4
Q9H2C1