Insufficient scRNA-seq data for expression of KLLN at single-cell level.
Insufficient scRNA-seq data for expression of KLLN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 96% | 71.78 | 85 / 89 | 70% | 1.54 | 629 / 901 |
ovary | 93% | 47.42 | 168 / 180 | 72% | 1.43 | 309 / 430 |
adrenal gland | 97% | 85.68 | 251 / 258 | 63% | 1.52 | 145 / 230 |
thymus | 99% | 71.34 | 645 / 653 | 60% | 1.19 | 364 / 605 |
breast | 100% | 103.20 | 458 / 459 | 57% | 1.03 | 635 / 1118 |
prostate | 97% | 59.43 | 238 / 245 | 53% | 0.87 | 268 / 502 |
brain | 99% | 80.88 | 2613 / 2642 | 46% | 0.67 | 321 / 705 |
intestine | 96% | 54.46 | 927 / 966 | 46% | 0.69 | 243 / 527 |
bladder | 100% | 59.81 | 21 / 21 | 41% | 0.67 | 208 / 504 |
stomach | 94% | 36.70 | 336 / 359 | 46% | 0.72 | 131 / 286 |
lung | 88% | 46.15 | 510 / 578 | 45% | 0.74 | 514 / 1155 |
pancreas | 84% | 29.00 | 275 / 328 | 47% | 0.73 | 83 / 178 |
uterus | 99% | 91.42 | 168 / 170 | 30% | 0.55 | 137 / 459 |
skin | 95% | 51.45 | 1715 / 1809 | 33% | 0.63 | 154 / 472 |
esophagus | 92% | 39.15 | 1335 / 1445 | 34% | 0.52 | 62 / 183 |
liver | 88% | 47.11 | 200 / 226 | 24% | 0.38 | 96 / 406 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.58 | 1 / 1 |
adipose | 100% | 114.49 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 99.46 | 240 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 66.28 | 1321 / 1335 | 0% | 0 | 0 / 0 |
muscle | 92% | 46.51 | 742 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 89% | 177.07 | 831 / 929 | 0% | 0 | 0 / 0 |
heart | 79% | 30.63 | 677 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 69% | 1.44 | 20 / 29 |
eye | 0% | 0 | 0 / 0 | 49% | 1.01 | 39 / 80 |
tonsil | 0% | 0 | 0 / 0 | 33% | 0.47 | 15 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006915 | Biological process | apoptotic process |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005730 | Cellular component | nucleolus |
GO_0003677 | Molecular function | DNA binding |
Gene name | KLLN |
Protein name | Killin |
Synonyms | |
Description | FUNCTION: DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single-stranded DNA. . |
Accessions | ENST00000635224.2 ENST00000644082.1 ENST00000445946.5 B2CW77 |